2-ANILINO NICOTINYL LINKED 2-AMINO BENZOTHIAZOLE CONJUGATES AND PROCESS FOR THE PREPARATION THEREOF
The present invention provides compounds of general formula A useful as potential anticancer agents against human cancer cell lines and apoptosis inducers. The present invention further provides a process for the preparation of 2-anilino nicotinyl linked 2-amino benzothiazole conjugates of general f...
Gespeichert in:
| Hauptverfasser: | , , , , , , , , , , , |
|---|---|
| Format: | Patent |
| Sprache: | eng ; fre |
| Schlagworte: | |
| Online-Zugang: | Volltext bestellen |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | |
| container_start_page | |
| container_title | |
| container_volume | |
| creator | SHASHI, BHUSHAN KHAN, MOHAMMED, NASEER, AHMED DAR, ABID, HAMID MONDHE, DILIP, MANIKRAO SAXENA, AJIT, JUMAR SRIKANTH, YELLAMELLI, VALLI, VENKATA KAMAL, AHMED SEHAR, IRUM CHASHOO, GOUSIA ASHRAF, MOHAMMED SINGH, SHASHANK, KUMAR SHARMA, PARDUMAN, RAJ |
| description | The present invention provides compounds of general formula A useful as potential anticancer agents against human cancer cell lines and apoptosis inducers. The present invention further provides a process for the preparation of 2-anilino nicotinyl linked 2-amino benzothiazole conjugates of general formula (A), wherein R1 = H or CI; R2 = H, OCH3 or F; R3 = H, OCH3, F or CI; R4=H, OCH3 or F and X= OCH3, F or N02.
L'invention concerne des composés de formule générale A pouvant servir d'agents anticancéreux potentiels agissant contre des lignées cellulaires de cancer humain et d'inducteurs d'apoptose. L'invention porte également sur un procédé de préparation de conjugés de 2-amino benzothiazole à liaison 2-anilino nicotinyl de formule générale (A), dans laquelle R1 = H ou CI; R2 = H, OCH3 ou F; R3 = H, OCH3, F ou CI; R4=H, OCH3 ou F et X= OCH3, F ou N02. |
| format | Patent |
| fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_WO2012111016A1</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>WO2012111016A1</sourcerecordid><originalsourceid>FETCH-epo_espacenet_WO2012111016A13</originalsourceid><addsrcrecordid>eNqNysEKgkAQxnEvHaJ6h4HOgmvQfVpnc8tmZN2IvIjIdooS7P1phR6g08eP_7dMhjxFtpVlAbZavOV7BZFnKiCmyxwOxK340mIrFYEWPl2P6KkB5AJqJ5qaBow48CVFU40OvRWe7UjMOlk8-ucUNr9dJVtDXpdpGN9dmMZ-CK_w6W6SZypXSmVqj2r33-sL2OM1AQ</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>2-ANILINO NICOTINYL LINKED 2-AMINO BENZOTHIAZOLE CONJUGATES AND PROCESS FOR THE PREPARATION THEREOF</title><source>esp@cenet</source><creator>SHASHI, BHUSHAN ; KHAN, MOHAMMED, NASEER, AHMED ; DAR, ABID, HAMID ; MONDHE, DILIP, MANIKRAO ; SAXENA, AJIT, JUMAR ; SRIKANTH, YELLAMELLI, VALLI, VENKATA ; KAMAL, AHMED ; SEHAR, IRUM ; CHASHOO, GOUSIA ; ASHRAF, MOHAMMED ; SINGH, SHASHANK, KUMAR ; SHARMA, PARDUMAN, RAJ</creator><creatorcontrib>SHASHI, BHUSHAN ; KHAN, MOHAMMED, NASEER, AHMED ; DAR, ABID, HAMID ; MONDHE, DILIP, MANIKRAO ; SAXENA, AJIT, JUMAR ; SRIKANTH, YELLAMELLI, VALLI, VENKATA ; KAMAL, AHMED ; SEHAR, IRUM ; CHASHOO, GOUSIA ; ASHRAF, MOHAMMED ; SINGH, SHASHANK, KUMAR ; SHARMA, PARDUMAN, RAJ</creatorcontrib><description>The present invention provides compounds of general formula A useful as potential anticancer agents against human cancer cell lines and apoptosis inducers. The present invention further provides a process for the preparation of 2-anilino nicotinyl linked 2-amino benzothiazole conjugates of general formula (A), wherein R1 = H or CI; R2 = H, OCH3 or F; R3 = H, OCH3, F or CI; R4=H, OCH3 or F and X= OCH3, F or N02.
L'invention concerne des composés de formule générale A pouvant servir d'agents anticancéreux potentiels agissant contre des lignées cellulaires de cancer humain et d'inducteurs d'apoptose. L'invention porte également sur un procédé de préparation de conjugés de 2-amino benzothiazole à liaison 2-anilino nicotinyl de formule générale (A), dans laquelle R1 = H ou CI; R2 = H, OCH3 ou F; R3 = H, OCH3, F ou CI; R4=H, OCH3 ou F et X= OCH3, F ou N02.</description><language>eng ; fre</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2012</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20120823&DB=EPODOC&CC=WO&NR=2012111016A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76516</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20120823&DB=EPODOC&CC=WO&NR=2012111016A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>SHASHI, BHUSHAN</creatorcontrib><creatorcontrib>KHAN, MOHAMMED, NASEER, AHMED</creatorcontrib><creatorcontrib>DAR, ABID, HAMID</creatorcontrib><creatorcontrib>MONDHE, DILIP, MANIKRAO</creatorcontrib><creatorcontrib>SAXENA, AJIT, JUMAR</creatorcontrib><creatorcontrib>SRIKANTH, YELLAMELLI, VALLI, VENKATA</creatorcontrib><creatorcontrib>KAMAL, AHMED</creatorcontrib><creatorcontrib>SEHAR, IRUM</creatorcontrib><creatorcontrib>CHASHOO, GOUSIA</creatorcontrib><creatorcontrib>ASHRAF, MOHAMMED</creatorcontrib><creatorcontrib>SINGH, SHASHANK, KUMAR</creatorcontrib><creatorcontrib>SHARMA, PARDUMAN, RAJ</creatorcontrib><title>2-ANILINO NICOTINYL LINKED 2-AMINO BENZOTHIAZOLE CONJUGATES AND PROCESS FOR THE PREPARATION THEREOF</title><description>The present invention provides compounds of general formula A useful as potential anticancer agents against human cancer cell lines and apoptosis inducers. The present invention further provides a process for the preparation of 2-anilino nicotinyl linked 2-amino benzothiazole conjugates of general formula (A), wherein R1 = H or CI; R2 = H, OCH3 or F; R3 = H, OCH3, F or CI; R4=H, OCH3 or F and X= OCH3, F or N02.
L'invention concerne des composés de formule générale A pouvant servir d'agents anticancéreux potentiels agissant contre des lignées cellulaires de cancer humain et d'inducteurs d'apoptose. L'invention porte également sur un procédé de préparation de conjugés de 2-amino benzothiazole à liaison 2-anilino nicotinyl de formule générale (A), dans laquelle R1 = H ou CI; R2 = H, OCH3 ou F; R3 = H, OCH3, F ou CI; R4=H, OCH3 ou F et X= OCH3, F ou N02.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2012</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNysEKgkAQxnEvHaJ6h4HOgmvQfVpnc8tmZN2IvIjIdooS7P1phR6g08eP_7dMhjxFtpVlAbZavOV7BZFnKiCmyxwOxK340mIrFYEWPl2P6KkB5AJqJ5qaBow48CVFU40OvRWe7UjMOlk8-ucUNr9dJVtDXpdpGN9dmMZ-CK_w6W6SZypXSmVqj2r33-sL2OM1AQ</recordid><startdate>20120823</startdate><enddate>20120823</enddate><creator>SHASHI, BHUSHAN</creator><creator>KHAN, MOHAMMED, NASEER, AHMED</creator><creator>DAR, ABID, HAMID</creator><creator>MONDHE, DILIP, MANIKRAO</creator><creator>SAXENA, AJIT, JUMAR</creator><creator>SRIKANTH, YELLAMELLI, VALLI, VENKATA</creator><creator>KAMAL, AHMED</creator><creator>SEHAR, IRUM</creator><creator>CHASHOO, GOUSIA</creator><creator>ASHRAF, MOHAMMED</creator><creator>SINGH, SHASHANK, KUMAR</creator><creator>SHARMA, PARDUMAN, RAJ</creator><scope>EVB</scope></search><sort><creationdate>20120823</creationdate><title>2-ANILINO NICOTINYL LINKED 2-AMINO BENZOTHIAZOLE CONJUGATES AND PROCESS FOR THE PREPARATION THEREOF</title><author>SHASHI, BHUSHAN ; KHAN, MOHAMMED, NASEER, AHMED ; DAR, ABID, HAMID ; MONDHE, DILIP, MANIKRAO ; SAXENA, AJIT, JUMAR ; SRIKANTH, YELLAMELLI, VALLI, VENKATA ; KAMAL, AHMED ; SEHAR, IRUM ; CHASHOO, GOUSIA ; ASHRAF, MOHAMMED ; SINGH, SHASHANK, KUMAR ; SHARMA, PARDUMAN, RAJ</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_WO2012111016A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2012</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>SHASHI, BHUSHAN</creatorcontrib><creatorcontrib>KHAN, MOHAMMED, NASEER, AHMED</creatorcontrib><creatorcontrib>DAR, ABID, HAMID</creatorcontrib><creatorcontrib>MONDHE, DILIP, MANIKRAO</creatorcontrib><creatorcontrib>SAXENA, AJIT, JUMAR</creatorcontrib><creatorcontrib>SRIKANTH, YELLAMELLI, VALLI, VENKATA</creatorcontrib><creatorcontrib>KAMAL, AHMED</creatorcontrib><creatorcontrib>SEHAR, IRUM</creatorcontrib><creatorcontrib>CHASHOO, GOUSIA</creatorcontrib><creatorcontrib>ASHRAF, MOHAMMED</creatorcontrib><creatorcontrib>SINGH, SHASHANK, KUMAR</creatorcontrib><creatorcontrib>SHARMA, PARDUMAN, RAJ</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>SHASHI, BHUSHAN</au><au>KHAN, MOHAMMED, NASEER, AHMED</au><au>DAR, ABID, HAMID</au><au>MONDHE, DILIP, MANIKRAO</au><au>SAXENA, AJIT, JUMAR</au><au>SRIKANTH, YELLAMELLI, VALLI, VENKATA</au><au>KAMAL, AHMED</au><au>SEHAR, IRUM</au><au>CHASHOO, GOUSIA</au><au>ASHRAF, MOHAMMED</au><au>SINGH, SHASHANK, KUMAR</au><au>SHARMA, PARDUMAN, RAJ</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>2-ANILINO NICOTINYL LINKED 2-AMINO BENZOTHIAZOLE CONJUGATES AND PROCESS FOR THE PREPARATION THEREOF</title><date>2012-08-23</date><risdate>2012</risdate><abstract>The present invention provides compounds of general formula A useful as potential anticancer agents against human cancer cell lines and apoptosis inducers. The present invention further provides a process for the preparation of 2-anilino nicotinyl linked 2-amino benzothiazole conjugates of general formula (A), wherein R1 = H or CI; R2 = H, OCH3 or F; R3 = H, OCH3, F or CI; R4=H, OCH3 or F and X= OCH3, F or N02.
L'invention concerne des composés de formule générale A pouvant servir d'agents anticancéreux potentiels agissant contre des lignées cellulaires de cancer humain et d'inducteurs d'apoptose. L'invention porte également sur un procédé de préparation de conjugés de 2-amino benzothiazole à liaison 2-anilino nicotinyl de formule générale (A), dans laquelle R1 = H ou CI; R2 = H, OCH3 ou F; R3 = H, OCH3, F ou CI; R4=H, OCH3 ou F et X= OCH3, F ou N02.</abstract><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext_linktorsrc |
| identifier | |
| ispartof | |
| issn | |
| language | eng ; fre |
| recordid | cdi_epo_espacenet_WO2012111016A1 |
| source | esp@cenet |
| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | 2-ANILINO NICOTINYL LINKED 2-AMINO BENZOTHIAZOLE CONJUGATES AND PROCESS FOR THE PREPARATION THEREOF |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-15T19%3A43%3A46IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=SHASHI,%20BHUSHAN&rft.date=2012-08-23&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EWO2012111016A1%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |