COMPOSITIONS COMPRISING A PI3K INHIBITOR AND A MEK INHIBITOR AND THEIR USE FOR TREATING CANCER

Methods of treating patients with cancer are provided, wherein the methods comprise administering to the patient an effective amount of a MEK inhibitor and an effective amount of a PI3K inhibitor. Compositions in which the MEK and PI3K inhibitors are combined also are described. L'invention con...

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Bibliographische Detailangaben
Hauptverfasser:	MCMILLAN, STUART, GARCIA-ESCHEVERRIA, CARLOS, OGDEN, JANET ANNE MEURER, DEBUSSCHE, LAURENT, VINCENT, LOIC, MA, JIANGUO
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:	Methods of treating patients with cancer are provided, wherein the methods comprise administering to the patient an effective amount of a MEK inhibitor and an effective amount of a PI3K inhibitor. Compositions in which the MEK and PI3K inhibitors are combined also are described. L'invention concerne des procédés de traitement de patients avec cancer, dans lesquels les procédés comprennent l'administration au patient d'une quantité efficace d'un inhibiteur de MEK et d'une quantité efficace d'un inhibiteur de PI3K. Les compositions dans lesquelles les inhibiteurs de MEK et de PI3K sont combinés sont aussi décrites.