PHENYL-HETEROARYL AMINE COMPOUNDS AND THEIR USES

The present invention provides a compound of formula (I): and pharmaceutically acceptable salts, enantiomers, stereoisomers, rotamers, tautomers, diastereomers, or racemates thereof. Also provided are methods of treating a disease or condition mediated by CDK9 using the compounds of Formula I, and p...

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Bibliographische Detailangaben
Hauptverfasser:	SUTTON, JAMES, WAN, LIFENG, PAN, YUE, BARSANTI, PAUL A, HU, CHENG, PFISTER, KEITH B, SENDZIK, MARTIN, ANTONIOS-MCCREA, WILLIAM R, MARTIN, ERIC J, JIN, XIANMING
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention provides a compound of formula (I): and pharmaceutically acceptable salts, enantiomers, stereoisomers, rotamers, tautomers, diastereomers, or racemates thereof. Also provided are methods of treating a disease or condition mediated by CDK9 using the compounds of Formula I, and pharmaceutical compositions comprising such compounds. La présente invention concerne un composé de formule (I) : et des sels, énantiomères, stéréoisomères, rotamères, tautomères, diastéréomères ou racémates pharmaceutiquement acceptables de ceux-ci. L'invention concerne également des méthodes de traitement d'une maladie ou d'un état à médiation par CDK9 à l'aide des composés de Formule (I), et des compositions pharmaceutiques comprenant de tels composés.