SUSTAINED RELEASE PHARMACEUTICAL COMPOSITIONS OF DONEPEZIL

The present invention relates to sustained release pharmaceutical compositions of donepezil or pharmaceutically acceptable salts thereof. The compositions of the invention are stable and provide sustained therapeutically effective plasma levels over a twenty four hour period with reduced incidences...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	HANDA, AJAYKUMAR, KULKARNI, SUSHRUT, KRISHNAJI, ROY, SUNILENDU, BHUSHAN
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:	The present invention relates to sustained release pharmaceutical compositions of donepezil or pharmaceutically acceptable salts thereof. The compositions of the invention are stable and provide sustained therapeutically effective plasma levels over a twenty four hour period with reduced incidences of cholinergic side effects. The invention also relates to process of making such compositions. L'invention concerne des compositions pharmaceutiques de donépézil ou des sels de celles-ci pharmaceutiquement acceptables à libération prolongée. Les compositions de l'invention sont stables et fournissent des niveaux soutenus de plasma thérapeutiquement efficaces pendant vingt quatre heures avec incidences limitées d'effets secondaires cholinergiques. L'invention concerne également un procédé de production des compositions.