NOVEL CIRCULAR MAMMALIAN RNA MOLECULES AND USES THEREOF

This invention is directed to isolated and purified nucleic acids encoding circular RNA comprising one or more ANRIL exons, methods for detecting such nucleic acids, and uses thereof. The invention provides methods for detecting ANRIL associated disorders such as atherosclerosis, related kits, and m...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	BURD, CHRISTIN, E, JECK, WILLIAM, R, SIEBOLD, ALEX, P, SHARPLESS, NORMAN, E, WANG, ZEFENG
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR COMPOSITIONS THEREOF CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES CULTURE MEDIA ENZYMOLOGY MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PROCESSES OF PREPARING SUCH COMPOSITIONS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	This invention is directed to isolated and purified nucleic acids encoding circular RNA comprising one or more ANRIL exons, methods for detecting such nucleic acids, and uses thereof. The invention provides methods for detecting ANRIL associated disorders such as atherosclerosis, related kits, and methods of screening for compounds to prevent or treat such disorders. La présente invention concerne des acides nucléiques isolés et purifiés codant pour un ARN circulaire comprenant un ou plusieurs exons ANRIL, des procédés de détection de ces acides nucléiques, et leurs utilisations. L'invention concerne des procédés de détection de troubles associés à ANRIL tels que l'athérosclérose, des kits associés, et des procédés de criblage de composés destinés à prévenir ou traiter ces troubles.