ANTI-ICAM-1 ANTIBODIES AND METHODS OF USE

Provided are anti-ICAM-1 antibodies or antibody fragments and methods of using them. In certain embodiments, anti-ICAM-1 antibodies or antibody fragments of the invention inhibit binding of human ICAM-1 to human rhinovirus, and do not substantially inhibit binding of human ICAM-1 to LFA1. L'inv...

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Bibliographische Detailangaben
Hauptverfasser: WELLS, EDWARD, STRAIN, MARTIN DOUGLAS, DODD, SARA, NEWTON, PHILIP ARTHUR, LOWE, DAVID CHRISTOPHER, VOUSDEN, KATHERINE ANN
Format: Patent
Sprache:eng ; fre
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Zusammenfassung:Provided are anti-ICAM-1 antibodies or antibody fragments and methods of using them. In certain embodiments, anti-ICAM-1 antibodies or antibody fragments of the invention inhibit binding of human ICAM-1 to human rhinovirus, and do not substantially inhibit binding of human ICAM-1 to LFA1. L'invention concerne des anticorps ou des fragments d'anticorps anti-ICAM-1 et leurs procédés d'utilisation. Dans certaines formes de réalisation, les anticorps ou les fragments d'anticorps anti-ICAM-1 de l'invention inhibent la liaison de l'ICAM-1 humain au rhinovirus humain, et n'inhibent pratiquement pas la liaison de l'ICAM-1 humain à LFA1.