NOVEL QUINOLINE ESTERS USEFUL FOR TREATING SKIN DISORDERS
Disclosed are quinoline esters of Formula (I):(I) which are useful as Liver X receptors (LXR) modulators. Pharmaceutical compositions containing quinoline esters of Formula (I) and the use of quinoline esters of Formula (I) in the safe treatment of various skin disorders are also disclosed. Methods...
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| creator | SINGHAUS, ROBERT NAGPAL, SUNIL BERNOTAS, RONALD CHARLES THOMPSON, CATHERINE |
| description | Disclosed are quinoline esters of Formula (I):(I) which are useful as Liver X receptors (LXR) modulators. Pharmaceutical compositions containing quinoline esters of Formula (I) and the use of quinoline esters of Formula (I) in the safe treatment of various skin disorders are also disclosed. Methods for preparing and using quinoline esters are further described.
L'invention concerne des esters de quinoléine de Formule (I):(I) qui sont utiles comme modulateurs des récepteurs X du foie (LXR). Elle concerne également des compositions pharmaceutiques contenant des esters de quinoléine de Formule (I) et l'utilisation d'esters de quinoléine de Formule (I) dans le traitement sûr de divers troubles cutanés. Elle concerne aussi des procédés de préparation et d'utilisation d'esters de quinoléine. |
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L'invention concerne des esters de quinoléine de Formule (I):(I) qui sont utiles comme modulateurs des récepteurs X du foie (LXR). Elle concerne également des compositions pharmaceutiques contenant des esters de quinoléine de Formule (I) et l'utilisation d'esters de quinoléine de Formule (I) dans le traitement sûr de divers troubles cutanés. Elle concerne aussi des procédés de préparation et d'utilisation d'esters de quinoléine.</description><language>eng ; fre</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2012</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20120112&DB=EPODOC&CC=WO&NR=2012004748A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76289</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20120112&DB=EPODOC&CC=WO&NR=2012004748A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>SINGHAUS, ROBERT</creatorcontrib><creatorcontrib>NAGPAL, SUNIL</creatorcontrib><creatorcontrib>BERNOTAS, RONALD CHARLES</creatorcontrib><creatorcontrib>THOMPSON, CATHERINE</creatorcontrib><title>NOVEL QUINOLINE ESTERS USEFUL FOR TREATING SKIN DISORDERS</title><description>Disclosed are quinoline esters of Formula (I):(I) which are useful as Liver X receptors (LXR) modulators. Pharmaceutical compositions containing quinoline esters of Formula (I) and the use of quinoline esters of Formula (I) in the safe treatment of various skin disorders are also disclosed. Methods for preparing and using quinoline esters are further described.
L'invention concerne des esters de quinoléine de Formule (I):(I) qui sont utiles comme modulateurs des récepteurs X du foie (LXR). Elle concerne également des compositions pharmaceutiques contenant des esters de quinoléine de Formule (I) et l'utilisation d'esters de quinoléine de Formule (I) dans le traitement sûr de divers troubles cutanés. Elle concerne aussi des procédés de préparation et d'utilisation d'esters de quinoléine.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2012</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZLD08w9z9VEIDPX08_fx9HNVcA0OcQ0KVggNdnUL9VFw8w9SCAlydQzx9HNXCPb29FNw8Qz2D3IBKuFhYE1LzClO5YXS3AzKbq4hzh66qQX58anFBYnJqXmpJfHh_kYGhkYGBibmJhaOhsbEqQIAVWwp8w</recordid><startdate>20120112</startdate><enddate>20120112</enddate><creator>SINGHAUS, ROBERT</creator><creator>NAGPAL, SUNIL</creator><creator>BERNOTAS, RONALD CHARLES</creator><creator>THOMPSON, CATHERINE</creator><scope>EVB</scope></search><sort><creationdate>20120112</creationdate><title>NOVEL QUINOLINE ESTERS USEFUL FOR TREATING SKIN DISORDERS</title><author>SINGHAUS, ROBERT ; NAGPAL, SUNIL ; BERNOTAS, RONALD CHARLES ; THOMPSON, CATHERINE</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_WO2012004748A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2012</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>SINGHAUS, ROBERT</creatorcontrib><creatorcontrib>NAGPAL, SUNIL</creatorcontrib><creatorcontrib>BERNOTAS, RONALD CHARLES</creatorcontrib><creatorcontrib>THOMPSON, CATHERINE</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>SINGHAUS, ROBERT</au><au>NAGPAL, SUNIL</au><au>BERNOTAS, RONALD CHARLES</au><au>THOMPSON, CATHERINE</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>NOVEL QUINOLINE ESTERS USEFUL FOR TREATING SKIN DISORDERS</title><date>2012-01-12</date><risdate>2012</risdate><abstract>Disclosed are quinoline esters of Formula (I):(I) which are useful as Liver X receptors (LXR) modulators. Pharmaceutical compositions containing quinoline esters of Formula (I) and the use of quinoline esters of Formula (I) in the safe treatment of various skin disorders are also disclosed. Methods for preparing and using quinoline esters are further described.
L'invention concerne des esters de quinoléine de Formule (I):(I) qui sont utiles comme modulateurs des récepteurs X du foie (LXR). Elle concerne également des compositions pharmaceutiques contenant des esters de quinoléine de Formule (I) et l'utilisation d'esters de quinoléine de Formule (I) dans le traitement sûr de divers troubles cutanés. Elle concerne aussi des procédés de préparation et d'utilisation d'esters de quinoléine.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | NOVEL QUINOLINE ESTERS USEFUL FOR TREATING SKIN DISORDERS |
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