PROCESS FOR THE PREPARATION OF N- [2 - (7 -METHOXY - 1 - NAPHTHYL) - ETHYL] ACETAMIDE AND NEW CRYSTALLINE FORM

PROCESS FOR THE PREPARATION OF N- [2 - (7 -METHOXY - 1 - NAPHTHYL) - ETHYL] ACETAMIDE AND NEW CRYSTALLINE FORM

A novel process for the preparation of N-[2-(7-methoxy-1-naphthyl)ethyl]acetamide, also known as agomelatine, Compound (I), from 7-methoxy-tetralone as starting material, and to a new crystalline form X of agomelatine. L'invention concerne un nouveau procédé de préparation de N-[2-(7-méthoxy-1-...

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Bibliographische Detailangaben
Hauptverfasser: MANGONE, CONSTANZA, PIA, GARCIA, MARIA, BEATRIZ, VECCHIOLI, ADRIANA, RUSTOY, EDUARDO, MIGUEL, TOMBARI, DORA, GRACIELA, LABRIOLA, RAFAEL, ALBERTO, BURTON, GERARDO
Format: Patent
Sprache:eng ; fre
Schlagworte:
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
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Zusammenfassung:A novel process for the preparation of N-[2-(7-methoxy-1-naphthyl)ethyl]acetamide, also known as agomelatine, Compound (I), from 7-methoxy-tetralone as starting material, and to a new crystalline form X of agomelatine. L'invention concerne un nouveau procédé de préparation de N-[2-(7-méthoxy-1-naphtyl)éthyl]acétamide, également appelé agomélatine, le composé (I), à partir de 7-méthoxy-tétralone comme matière première, et une nouvelle forme cristalline X d'agomélatine.