DENDRIMERS AS NON-VIRAL VEHICLES FOR GENE THERAPY

The invention relates to novel compounds having general formula (I), (II) and (III) for use in gene therapy as non-viral vehicles and to the use thereof for the development of a drug. The invention also relates to the method for the synthesis of said compounds having general formula (I), (II) and (I...

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Hauptverfasser: RUBIO CARRERO, NOELIA, SANCHEZ VERDU, MA DEL PRADO, PEREZ MARTINEZ, FRANCISCO CARLOS, RODRIGUEZ LOPEZ, JULIAN, VAZQUEZ FERNANDEZ-PACHECO, ESTER, CAMPO RODRIGO, ANA, GUERRA NAVARRO, FRANCISCO JAVIER, HERRERO CHAMORRO, MARIA ANTONIA, GARCIA MARTINEZ, JOAQUIN CALIXTO, CENA CALLEJO, VALENTIN, MERINO GUIJARRO, SONIA
Format: Patent
Sprache:eng ; fre ; spa
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Zusammenfassung:The invention relates to novel compounds having general formula (I), (II) and (III) for use in gene therapy as non-viral vehicles and to the use thereof for the development of a drug. The invention also relates to the method for the synthesis of said compounds having general formula (I), (II) and (III). La presente invención se refiere a nuevos compuestos de fórmula general (I), (II) y (III) para su uso en terapia génica como vehículos no virales y su uso para la elaboración de un medicamento. Además se describe el procedimiento de síntesis de dichos compuestos de fórmula general (I), (II) y (III). La présente invention concerne de nouveaux composés de formule générale (I), (II) et (III) utilisés en thérapie génique comme véhicules non viraux et dans l'élaboration d'un médicament. Elle concerne, en outre, un procédé de synthèse de ces composés de formule générale (I), (II) et (III).