TUMOUR TREATMENT AGENTS AND METHOD

N1-(3-Methoxypropyl)-2-(pyridylmethylidene)-hydrazine-1-carbothioamide (I) and its Cu2+, Pd2+ and Pt2+ complexes are effective anti-tumor agents. Also disclosed are compositions comprising (I) and its Cu2+, Pd2+ and Pt2+ complexes, and the use of the compositions in the treatment of malignant tumors...

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Bibliographische Detailangaben
Hauptverfasser:	NYGREN, PETER, GULLBO, JOAKIM, LARSSON, ROLF, WESTMAN, GUNNAR
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	N1-(3-Methoxypropyl)-2-(pyridylmethylidene)-hydrazine-1-carbothioamide (I) and its Cu2+, Pd2+ and Pt2+ complexes are effective anti-tumor agents. Also disclosed are compositions comprising (I) and its Cu2+, Pd2+ and Pt2+ complexes, and the use of the compositions in the treatment of malignant tumors. La présente invention concerne le N1-3-méthoxypropyl)-2-(pyridyl- méthylidène)-hydrazine-1-carbothioamide (I) et ses complexes de Cu2+, Pd2+ et Pt2+, efficaces en tant qu'agents antitumoraux. L'invention concerne également des compositions comprenant (I) et ses complexes de Cu2+, Pd2+ et Pt2+, ainsi que l'utilisation des compositions dans le traitement de tumeurs malignes.