IMIDAZOQUINOLINES WHICH ACT VIA TOLL - LIKE RECEPTORS (TLR)

The present invention provides compounds of formula (I): wherein Ra, Rb, Rc, R1, R2, R3, X1, Y1, Z1, A, n and m are as defined in the specification, and pharmaceutically acceptable salts thereof, as well as processes for their preparation, pharmaceutical compositions containing them and their use in...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	KUREBAYASHI, HIROTAKA, NAKAMURA, TOMOAKI, TOJO, SHINGO, ISOBE, YOSHIAKI, KASAI, MAI
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention provides compounds of formula (I): wherein Ra, Rb, Rc, R1, R2, R3, X1, Y1, Z1, A, n and m are as defined in the specification, and pharmaceutically acceptable salts thereof, as well as processes for their preparation, pharmaceutical compositions containing them and their use in therapy. L'invention concerne des composés de formule (I) : dans laquelle Ra, Rb, Rc, R1, R2, R3, X1, Y1, Z1, A, n et m sont tels que définis dans la description, ainsi que des sels pharmaceutiquement acceptables de ceux-ci. L'invention concerne également des procédés de préparation de ces composés, des compositions pharmaceutiques les contenant, ainsi que leur utilisation thérapeutique.