CARBOXYLIC ACID ANALOGS AS GLYCOGEN SYNTHASE ACTIVATORS

CARBOXYLIC ACID ANALOGS AS GLYCOGEN SYNTHASE ACTIVATORS

Provided herein are compounds of the formula (I): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of metabolic diseases and d...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: HAYDEN, STUART, BOLIN, DAVID ROBERT, THAKKAR, KSHITIJ CHHABILBHAI, QIAN, YIMIN
Format: Patent
Sprache:eng ; fre
Schlagworte:
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:Provided herein are compounds of the formula (I): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of metabolic diseases and disorders such as, for example, type II diabetes mellitus. La présente invention porte sur des composés représentés par la formule (I) : ainsi que sur des sels pharmaceutiquement acceptables de ceux-ci, dont les substituants de la formule sont tels que décrits dans la description. Ces composés, et les compositions pharmaceutiques les contenant, sont utiles pour le traitement de maladies et troubles métaboliques tels que, par exemple, le diabète de type II.