METHOD FOR PREPARING N-SUCCINIMIDYL N-BIOTINYL-6-AMINOCAPROATE

The invention relates to a method for preparing N-succinimidyl N-biotinyl-6-aminocaproate, characterised in that said method includes a step of activating N-biotinyl-6-aminocaproic acid in the form of a mixed anhydride, followed by coupling said mixed anhydride with N-hydroxysuccinimide. Procédé de...

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Hauptverfasser: TROUILLEUX, PATRICK, SOLE, RAPHAEL, POTIER, PIERRE
Format: Patent
Sprache:eng ; fre
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Zusammenfassung:The invention relates to a method for preparing N-succinimidyl N-biotinyl-6-aminocaproate, characterised in that said method includes a step of activating N-biotinyl-6-aminocaproic acid in the form of a mixed anhydride, followed by coupling said mixed anhydride with N-hydroxysuccinimide. Procédé de préparation du N-biotinyl-6-aminocaproate de N-succinimidyle, caractérisé en ce qu'il comprend une étape d'activation, sous forme d'anhydride mixte, de l'acide N-biotinyl-6-aminocaproïque, suivie du couplage dudit anhydride mixte avec le N-hydroxysuccinimide.