COMPOUNDS AS LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS

Described herein are compounds that are antagonists of lysophosphatidic receptor(s). Also described are pharmaceutical compositions and medicaments that include the compounds described herein, as well as methods of using such antagonists, alone and in combination with other compounds, for treating L...

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Bibliographische Detailangaben
Hauptverfasser:	HUTCHINSON, JOHN, HOWARD, STOCK, NICHOLAS, SIMON, SEIDERS, THOMAS, JON, CLARK, RYAN, COATE, HEATHER, RENEE, STEARNS, BRIAN, ANDREW, TRUONG, YEN, PHAM, ARRUDA, JEANNIE, M, VOLKOTS, DEBORAH, ZHAO, LUCY, WANG, BOWEI, SCOTT, JILL, MELISSA
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	Described herein are compounds that are antagonists of lysophosphatidic receptor(s). Also described are pharmaceutical compositions and medicaments that include the compounds described herein, as well as methods of using such antagonists, alone and in combination with other compounds, for treating LPA-dependent or LPA-mediated conditions or diseases. L'invention concerne des composés qui sont des antagonistes du ou des récepteurs lysophosphatidiques. L'invention concerne également des compositions pharmaceutiques et des médicaments qui comprennent les composés de l'invention, ainsi que des procédés d'utilisation de ces antagonistes, seuls ou en combinaison avec d'autres composés, pour le traitement d'états ou de pathologies dépendant de LPA ou induits par LPA.