MONOCONJUGATED CHITOSANS AS DELIVERY AGENTS FOR SMALL INTERFERING NUCLEIC ACIDS

Conjugates are provided, an exemplary conjugating having a single water-soluble, non-peptidic polymer, such as a poly( ethylene oxide), attached to a chitosan. Complexes of small interfering nucleic acids formed with such conjugates as well as small interfering nucleic acids attached to such conjuga...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: YOUSO, PATRICK, D, MCMANUS, SAMUEL, P, KOZLOWSKI, ANTONI
Format: Patent
Sprache:eng ; fre
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