PHARMACEUTICAL COMPOSITION CONTAINING DOPAMINE RECEPTOR AGONIST

A pharmaceutical composition containing dopamine receptor agonist, in specific, a solid oral dosage form containing ropinirole or the pharmaceutically acceptable salts thereof, is disclosed. Said composition contains, in terms of the total weight of the dosage form, 0.1%-20.0% of ropinirole or its salts, 0.5%-20% calcium carboxymethylcellulose, 70.0%-98.0% fillers, 0.0%-5.0% binders, 0.0%-3.0% glidants and 0.1%-1.5% lubricants. The preparation method thereof is to mix ropinirole or its salts, calcium carboxymethylcellulose, fillers, binders, glidants and lubricants, then compress the raw materials mixture to tablets. Alternatively, the preparation method is to make granules by dry granulating or wet granulating followed by drying process, then to compress the result mixture to tablets after lubricant is added to. The present invention can significantly improve the stability and quality of the product, and the storage requirement thereof would be less strict. L'invention porte sur une composition pharmaceutiqu