TRIAZINE DERIVATES FOR USE IN THE TREATMENT OF MALARIA

The invention provides compounds of formula (I), in which R1 and R2 are independently selected from H, alkyl, aryl and heteroaryl, or R1 and R2 together form a C5-C7 ring, R3-R7 are independently selected from H, halogen, alkyl and alkoxy, X is (CH2)n in which n is 0-5, Y is selected from CH2, NR8,...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	GRAVESTOCK, DAVID, LOURENS, ANNA, CATHARINA UYS, ROUSSEAU, AMANDA, LOUISE
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	The invention provides compounds of formula (I), in which R1 and R2 are independently selected from H, alkyl, aryl and heteroaryl, or R1 and R2 together form a C5-C7 ring, R3-R7 are independently selected from H, halogen, alkyl and alkoxy, X is (CH2)n in which n is 0-5, Y is selected from CH2, NR8, O or S in which R8 is H or alkyl, salts thereof and stereoisomers thereof, for the prophylaxis or treatment of malaria. Cette invention concerne des composés de formule I, des sels et des stéréoisomères de celui-ci pour prévenir ou traiter la malaria. Dans la formule I, R1 et R2 sont indépendamment choisis parmi H, un groupe alkyle, aryle et héteroaryle, ou R1 et R2 forment ensemble un cycle C5-C7, R3-R7 sont indépendamment choisis parmi H, un atome d'halogène, un groupe alkyle et alcoxy, X est (CH2)n, n valant de 0 à 5, Y est choisi parmi CH2, NR8, O ou S, R8 étant H ou un groupe alkyle.