ORAL DOSAGE FORMS

Aspects of the present invention are directed to oral dosage forms comprising a compressed microtablet, wherein said microtablet has a major dimension that is between about 0.25 mm and about 1.0 mm and comprises at least about 0.01 weight percent of at least one pharmaceutically active agent that is...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: BUBB, GARY, BEHL, CHARANJIT, R, ERKOBONI, DAVID, F, DICK, CHRISTOPHER, C
Format: Patent
Sprache:eng ; fre
Schlagworte:
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Aspects of the present invention are directed to oral dosage forms comprising a compressed microtablet, wherein said microtablet has a major dimension that is between about 0.25 mm and about 1.0 mm and comprises at least about 0.01 weight percent of at least one pharmaceutically active agent that is distributed substantially throughout said microtablet. Additional aspects of the present invention are directed to methods for producing compressed microtablets having a major dimension that is between about 0.25 mm and about 1.0 mm. La présente invention porte sur des formes posologiques orales comprenant un micro-comprimé, le micro-comprimé ayant une dimension principale comprise entre environ 0,25 mm et environ 1,0 mm, et comprenant au moins environ 0,01 % en poids d'au moins un agent pharmaceutiquement actif sensiblement réparti dans ledit micro-comprimé. La présente invention porte de plus sur des procédés de production de micro-comprimés comprimés ayant une dimension principale comprise entre environ 0,25 mm et environ 1,0 mm.