PROCESSES FOR PREPARING CRYSTALLINE FORMS

The present invention relates to intermediates and their preparation, for use in the manufacture of pure dasatinib, in particularly dasatinib monohydrate and anhydrous dasatinib. The invention also relates to pharmaceutical compositions comprising pure dasatinib and their use in the treatment of can...

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Hauptverfasser: GORE, VINAYAK GOVIND, VIJAYKAR, PRIYESH SURENDRA, BAGUL, AMIT, PATKAR, LAXMIKANT, EDAKE, MAHESH
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creator GORE, VINAYAK GOVIND
VIJAYKAR, PRIYESH SURENDRA
BAGUL, AMIT
PATKAR, LAXMIKANT
EDAKE, MAHESH
description The present invention relates to intermediates and their preparation, for use in the manufacture of pure dasatinib, in particularly dasatinib monohydrate and anhydrous dasatinib. The invention also relates to pharmaceutical compositions comprising pure dasatinib and their use in the treatment of cancer. L'invention concerne des intermédiaires et leur élaboration, aux fins d'utilisation dans la fabrication de dasatinib pur, en particulier le monohydrate de dasatinib et le dasatinib anhydre. L'invention concerne aussi des compositions pharmaceutiques renfermant du dasatinib pur et leur utilisation dans le traitement du cancer.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title PROCESSES FOR PREPARING CRYSTALLINE FORMS
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