PROCESSES FOR PREPARING CRYSTALLINE FORMS

The present invention relates to intermediates and their preparation, for use in the manufacture of pure dasatinib, in particularly dasatinib monohydrate and anhydrous dasatinib. The invention also relates to pharmaceutical compositions comprising pure dasatinib and their use in the treatment of can...

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Bibliographische Detailangaben
Hauptverfasser:	GORE, VINAYAK GOVIND, VIJAYKAR, PRIYESH SURENDRA, BAGUL, AMIT, PATKAR, LAXMIKANT, EDAKE, MAHESH
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention relates to intermediates and their preparation, for use in the manufacture of pure dasatinib, in particularly dasatinib monohydrate and anhydrous dasatinib. The invention also relates to pharmaceutical compositions comprising pure dasatinib and their use in the treatment of cancer. L'invention concerne des intermédiaires et leur élaboration, aux fins d'utilisation dans la fabrication de dasatinib pur, en particulier le monohydrate de dasatinib et le dasatinib anhydre. L'invention concerne aussi des compositions pharmaceutiques renfermant du dasatinib pur et leur utilisation dans le traitement du cancer.