BETA-LACTAMASE INHIBITORS

Disclosed herein are a-aminoboronic acids and their derivatives which act as inhibitors of beta-lactamases. Also disclosed herein are pharmaceutical compositions comprising a-aminoboronic acids and methods of use thereof. La présente invention concerne des acides a-aminoboroniques et leurs dérivés,...

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Bibliographische Detailangaben
Hauptverfasser:	TIRUNAHARI, PAVAN, KUMAR, PEVEAR, DANIEL, GOSWAMI, RAJESH, XU, HONGYU, JACKSON, RANDY, W, LESSEN, THOMAS, BURNS, CHRISTOPHER, J, LI, WEIPING
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	Disclosed herein are a-aminoboronic acids and their derivatives which act as inhibitors of beta-lactamases. Also disclosed herein are pharmaceutical compositions comprising a-aminoboronic acids and methods of use thereof. La présente invention concerne des acides a-aminoboroniques et leurs dérivés, lesquels agissent comme inhibiteurs de béta-lactamases. L'invention concerne également des compositions pharmaceutiques comprenant les acides a-aminoboroniques et leurs procédés d'utilisation.