INDOLE DERIVATIVE MODULATORS OF THE ALPHA 7 NACHR

This invention relates to modulation of the a7 nicotinic acetylcholine receptor (nAChR) by a compound of formula (I) or a salt thereof: wherein R1 is imidazolyl, pyridinyl or pyrimidinyl, any of which is optionally substituted by one group independently selected from C1-3alkyl and C1-3alkoxy. Cette...

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Bibliographische Detailangaben
1. Verfasser:	DINNELL, KEVIN
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	This invention relates to modulation of the a7 nicotinic acetylcholine receptor (nAChR) by a compound of formula (I) or a salt thereof: wherein R1 is imidazolyl, pyridinyl or pyrimidinyl, any of which is optionally substituted by one group independently selected from C1-3alkyl and C1-3alkoxy. Cette invention porte sur la modulation du récepteur nicotinique a7 de l'acétylcholine (nAChR) par un composé de formule (I) ou un sel de celui-ci : où R1 est imidazolyle, pyridinyle ou pyrimidinyle, n'importe lequel d'entre eux étant facultativement substitué par un groupe indépendamment choisi parmi alkyle en C1-3 et alcoxy en C1-3.