DOSING REGIMEN FOR THE TREATMENT OF ALZHEIMER'S DISEASE WITH SULFONYL FLUORIDES

The present invention provides for improved dosing regimens for the provision of sulfonyl fluorides, such a methanesulfonyl fluoride (MSF) to subjects suffering from Alzheimer's Disease (AD). The methods rely on an alternating day dosing scheme that avoids toxicity associated with a daily dosin...

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Hauptverfasser:	PERICLE, FEDERICA, BRAGLIA, ENRICO
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention provides for improved dosing regimens for the provision of sulfonyl fluorides, such a methanesulfonyl fluoride (MSF) to subjects suffering from Alzheimer's Disease (AD). The methods rely on an alternating day dosing scheme that avoids toxicity associated with a daily dosing regimen. L'invention concerne des schémas posologiques améliorés permettant d'administrer des fluorures de sulfonyle, tels qu'un fluorure de méthanesulfonyle (MSF) à des sujets souffrant de la maladie d'Alzheimer (MA). Les procédés reposent sur un schéma posologique quotidien alterné qui évite la toxicité associée à un schéma posologique quotidien.