PROCESS FOR PURIFYING ESLICARBAZEPINE ACETATE

PROCESS FOR PURIFYING ESLICARBAZEPINE ACETATE

A process for purifying eslicarbazepine acetate is provided The crystalline particles of eslicarbazepine acetate having a median particle size between 5 µm and 20 µm and a specific surface area of from 0.1 m2/g to 10 m2/g as measured by B.E.T. method are obtained Eslicarbazepine acetate having purit...

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Hauptverfasser: KOILPILLAI, JOSEPH PRABAHAR, LIMBEKAR, NAGESH DEVIDASRAO, SAWANT, SACHIN BAPURAO, KULKARNI, PRAVIN BHALCHANDRA
Format: Patent
Sprache:eng ; fre
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:A process for purifying eslicarbazepine acetate is provided The crystalline particles of eslicarbazepine acetate having a median particle size between 5 µm and 20 µm and a specific surface area of from 0.1 m2/g to 10 m2/g as measured by B.E.T. method are obtained Eslicarbazepine acetate having purity greater than 99.0% as measured by high performance liquid chromatography and a pharmaceutical composition containing the same are also provided. La présente invention concerne la purification et la taille particulaire de l'acétate d'eslicarbazépine. L'invention concerne également les caractéristiques physiques de l'acétate d'eslicarbazépine à l'état solide, et des compositions pharmaceutiques le contenant.