TOSYLATE SALT OF A 5-PYRAZOLYL-2-PYRIDONE DERIVATIVE, USEFUL IN THE TREATMENT OF COPD

6-Methyl-5-(I -methyl-1H-pyrazol-5-yl)-N-{ [5-(methylsulfonyl)pyridin-2-yl]methyl }-2-oxo-1-[3-(trifluoromethyl)phenyl]-1,2-dihydropyridine-3-carboxamide 4-methylbenzenesulfonate and a novel crystalline form thereof are disclosed together with processes for preparing such salt and form, pharmaceutic...

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Bibliographische Detailangaben
Hauptverfasser:	KLINGSTEDT, PER, TOMAS, LOENN, HANS, ROLAND, ZUBAN, ROBERT, NICKLASSON, HELENA, ALCARAZ, MARIE-LYNE, WATTS, ANDREW, JAMES, BRIGGNER, LARS-ERIK, NIXON, ROBERT, ANTHONY
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	6-Methyl-5-(I -methyl-1H-pyrazol-5-yl)-N-{ [5-(methylsulfonyl)pyridin-2-yl]methyl }-2-oxo-1-[3-(trifluoromethyl)phenyl]-1,2-dihydropyridine-3-carboxamide 4-methylbenzenesulfonate and a novel crystalline form thereof are disclosed together with processes for preparing such salt and form, pharmaceutical compositions comprising such a form, and the use of such a salt and form in therapy. La présente invention concerne le 6-méthyl-5-(I-méthyl-1 H-pyrazol-5-yl)-N-{[5-(méthylsulfonyl)pyridin-2-yl]méthyl}-2-oxo-1-[3-(trifluorométhyl)phényl]-1,2-dihydropyridine-3-carboxamide 4-méthylbenzènesulfonate et sa nouvelle forme cristalline ainsi que des procédés de préparation dudit sel et de ladite forme, des compositions pharmaceutiques comprenant ladite forme, et l'utilisation dudit sel et de ladite forme en traitement.