METHOD AND SYSTEMS FOR ENRICHMENT OF TARGET GENOMIC SEQUENCES

The present invention provides methods and systems for targeted nucleic acid sequence enrichment in a sample. In particular, the present invention provides for enriching for targeted nucleic acid sequences during hybridizations in hybridization assays by first depleting non-target nucleic acid seque...

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Bibliographische Detailangaben
Hauptverfasser: ALBERT, THOMAS, MARRIONE, PAUL, RICHMOND, TODD, JEDDELOH, JEFFREY, RODESCH, MATTHEW, GERHARDT, DANIEL
Format: Patent
Sprache:eng ; fre
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Zusammenfassung:The present invention provides methods and systems for targeted nucleic acid sequence enrichment in a sample. In particular, the present invention provides for enriching for targeted nucleic acid sequences during hybridizations in hybridization assays by first depleting non-target nucleic acid sequences. L'invention concerne des procédés et des systèmes d'enrichissement de séquences d'acide nucléique ciblées dans un échantillon. Elle concerne permet en particulier d'enrichir des séquences d'acide nucléique ciblées pendant des hybridations produites lors d'essais d'hybridation, par l'appauvrissement initial de séquences d'acide nucléique non ciblées.