CARJBAMOYLPHOSPHONATES AS INHIBITORS AND USES THEREOF

The present invention relates to novel metalloproteinase inhibitors having an aryloxybenzenesulfonamide moiety and a carbamoylphosphonic acid moiety, to pharmaceutical compositions comprising them, and to their uses in the prevention and/or treatment of disease or disorder associated with MMP. La pr...

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Bibliographische Detailangaben
Hauptverfasser:	BREUER, ELI, FRANT, JULIA, HOFFMAN, AMNON, AINELLY, VEERENDHAR, REICH, REUVEN
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention relates to novel metalloproteinase inhibitors having an aryloxybenzenesulfonamide moiety and a carbamoylphosphonic acid moiety, to pharmaceutical compositions comprising them, and to their uses in the prevention and/or treatment of disease or disorder associated with MMP. La présente invention porte sur de nouveaux inhibiteurs de métalloprotéinase comprenant une fraction aryloxybenzènesulfonamide et une fraction acide carbamoylphosphonique, sur des compositions pharmaceutiques les comprenant et sur leurs utilisations dans la prévention et/ou le traitement d'une maladie ou d'un trouble associé aux MMP.