STARCH COPOLYMERS AND NANOPARTICLES THEREOF FOR DRUG DELIVERY SYSTEMS

The present invention relates to starch Copolymer comprising starch as a backbone molecule, a covalently bound linker and a polymerized chain of monomers comprising at least one olefin group bound to the linker, wherein the degree of substitution of hydroxy-groups of the backbone is in the range of...

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Bibliographische Detailangaben
Hauptverfasser:	KELLER, HARALD, WALTER, HANS-MICHAEL, STAUNER, THOMAS, LORETZ, BRIGITTA, NAFEE, NOHA, HIROSUE, MASAYUKI, SCHNELLER, ARNOLD, WENZ, GERHARD
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY COMPOSITIONS BASED THEREON COMPOSITIONS OF MACROMOLECULAR COMPOUNDS DERIVATIVES THEREOF HUMAN NECESSITIES HYGIENE MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVINGCARBON-TO-CARBON UNSATURATED BONDS MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC MACROMOLECULAR COMPOUNDS POLYSACCHARIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES THEIR PREPARATION OR CHEMICAL WORKING-UP
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Beschreibung
Zusammenfassung:	The present invention relates to starch Copolymer comprising starch as a backbone molecule, a covalently bound linker and a polymerized chain of monomers comprising at least one olefin group bound to the linker, wherein the degree of substitution of hydroxy-groups of the backbone is in the range of 0.05 to 3, a method of preparation, nanoparticles comprising the copolymers, their preparation and their use for the preparation of drug delivery systems. La présente invention concerne un copolymère d'amidon comprenant de l'amidon comme molécule squelette, un lieur lié de manière covalente et une chaîne polymérisée de monomères comprenant au moins un groupe oléfinique lié au lieur, le degré de substitution des groupes hydroxy du squelette étant dans la plage allant de 0,05 à 3, un procédé de préparation, des nanoparticules comprenant les copolymères, leur préparation et leur utilisation pour la préparation des systèmes d'administration de médicaments.