PREPARATION OF 3-(2-HYDROXY ETHYL)-9-HYDROXY-2-METHYL-4H-PYRIDO-[1,2-A]-PYRIMIDIN-4-ONE OR ITS ACID ADDITION SALT
The invention relates to an improved process for preparation of 3-(2-hydroxy ethyl)-9- hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one or its acid addition salt and its conversion to paliperidone or its acid addition salt without involving the use of an acid catalyst. La présente invention concerne...
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| creator | BAPAT, UDAY, RAJARAM SHARMA, ARUN, OMPRAKASH MALIK, VINEET JAIN, SUDHIR, HUKAMCHAND PARIKH, SANJAY, NATVARLAL KHAMAR, BAKULESH, MAFATLAL DESAI, BHARAT, RAMCHANDRA SODAGAR, KEVAL, RAMESHCHANDRA |
| description | The invention relates to an improved process for preparation of 3-(2-hydroxy ethyl)-9- hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one or its acid addition salt and its conversion to paliperidone or its acid addition salt without involving the use of an acid catalyst.
La présente invention concerne un procédé amélioré de synthèse de la 3-(2-hydroxyéthyl)-9-hydroxy-2-méthyl-4H-pyrido[1,2-a]pyrimidin-4-one ou de son sel d'addition acide et sa conversion en palipéridone ou en son sel d'addition acide sans impliquer de catalyseur acide. |
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La présente invention concerne un procédé amélioré de synthèse de la 3-(2-hydroxyéthyl)-9-hydroxy-2-méthyl-4H-pyrido[1,2-a]pyrimidin-4-one ou de son sel d'addition acide et sa conversion en palipéridone ou en son sel d'addition acide sans impliquer de catalyseur acide.</description><language>eng ; fre</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; METALLURGY ; ORGANIC CHEMISTRY</subject><creationdate>2010</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20100722&DB=EPODOC&CC=WO&NR=2010082111A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20100722&DB=EPODOC&CC=WO&NR=2010082111A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>BAPAT, UDAY, RAJARAM</creatorcontrib><creatorcontrib>SHARMA, ARUN, OMPRAKASH</creatorcontrib><creatorcontrib>MALIK, VINEET</creatorcontrib><creatorcontrib>JAIN, SUDHIR, HUKAMCHAND</creatorcontrib><creatorcontrib>PARIKH, SANJAY, NATVARLAL</creatorcontrib><creatorcontrib>KHAMAR, BAKULESH, MAFATLAL</creatorcontrib><creatorcontrib>DESAI, BHARAT, RAMCHANDRA</creatorcontrib><creatorcontrib>SODAGAR, KEVAL, RAMESHCHANDRA</creatorcontrib><title>PREPARATION OF 3-(2-HYDROXY ETHYL)-9-HYDROXY-2-METHYL-4H-PYRIDO-[1,2-A]-PYRIMIDIN-4-ONE OR ITS ACID ADDITION SALT</title><description>The invention relates to an improved process for preparation of 3-(2-hydroxy ethyl)-9- hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one or its acid addition salt and its conversion to paliperidone or its acid addition salt without involving the use of an acid catalyst.
La présente invention concerne un procédé amélioré de synthèse de la 3-(2-hydroxyéthyl)-9-hydroxy-2-méthyl-4H-pyrido[1,2-a]pyrimidin-4-one ou de son sel d'addition acide et sa conversion en palipéridone ou en son sel d'addition acide sans impliquer de catalyseur acide.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2010</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNjbEKwjAURbs4iPoPD1wUfJCkHXR8NCkJtE1JAxpESpE4iVbq_yMU3Z0O93DhzJNX41RDjryxNdgCUtwI1EE6ewqgvA7lFg8_gQKryWGmsQnOSItnvhNIl2lWRpoaM7S1AuvA-BYoNxJISjMFWir9Mpnd-vsYV18uknWhfK4xDs8ujkN_jY_47o5WMM7YXnDOiaf_vT5oIjf7</recordid><startdate>20100722</startdate><enddate>20100722</enddate><creator>BAPAT, UDAY, RAJARAM</creator><creator>SHARMA, ARUN, OMPRAKASH</creator><creator>MALIK, VINEET</creator><creator>JAIN, SUDHIR, HUKAMCHAND</creator><creator>PARIKH, SANJAY, NATVARLAL</creator><creator>KHAMAR, BAKULESH, MAFATLAL</creator><creator>DESAI, BHARAT, RAMCHANDRA</creator><creator>SODAGAR, KEVAL, RAMESHCHANDRA</creator><scope>EVB</scope></search><sort><creationdate>20100722</creationdate><title>PREPARATION OF 3-(2-HYDROXY ETHYL)-9-HYDROXY-2-METHYL-4H-PYRIDO-[1,2-A]-PYRIMIDIN-4-ONE OR ITS ACID ADDITION SALT</title><author>BAPAT, UDAY, RAJARAM ; SHARMA, ARUN, OMPRAKASH ; MALIK, VINEET ; JAIN, SUDHIR, HUKAMCHAND ; PARIKH, SANJAY, NATVARLAL ; KHAMAR, BAKULESH, MAFATLAL ; DESAI, BHARAT, RAMCHANDRA ; SODAGAR, KEVAL, RAMESHCHANDRA</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_WO2010082111A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2010</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><toplevel>online_resources</toplevel><creatorcontrib>BAPAT, UDAY, RAJARAM</creatorcontrib><creatorcontrib>SHARMA, ARUN, OMPRAKASH</creatorcontrib><creatorcontrib>MALIK, VINEET</creatorcontrib><creatorcontrib>JAIN, SUDHIR, HUKAMCHAND</creatorcontrib><creatorcontrib>PARIKH, SANJAY, NATVARLAL</creatorcontrib><creatorcontrib>KHAMAR, BAKULESH, MAFATLAL</creatorcontrib><creatorcontrib>DESAI, BHARAT, RAMCHANDRA</creatorcontrib><creatorcontrib>SODAGAR, KEVAL, RAMESHCHANDRA</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>BAPAT, UDAY, RAJARAM</au><au>SHARMA, ARUN, OMPRAKASH</au><au>MALIK, VINEET</au><au>JAIN, SUDHIR, HUKAMCHAND</au><au>PARIKH, SANJAY, NATVARLAL</au><au>KHAMAR, BAKULESH, MAFATLAL</au><au>DESAI, BHARAT, RAMCHANDRA</au><au>SODAGAR, KEVAL, RAMESHCHANDRA</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>PREPARATION OF 3-(2-HYDROXY ETHYL)-9-HYDROXY-2-METHYL-4H-PYRIDO-[1,2-A]-PYRIMIDIN-4-ONE OR ITS ACID ADDITION SALT</title><date>2010-07-22</date><risdate>2010</risdate><abstract>The invention relates to an improved process for preparation of 3-(2-hydroxy ethyl)-9- hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one or its acid addition salt and its conversion to paliperidone or its acid addition salt without involving the use of an acid catalyst.
La présente invention concerne un procédé amélioré de synthèse de la 3-(2-hydroxyéthyl)-9-hydroxy-2-méthyl-4H-pyrido[1,2-a]pyrimidin-4-one ou de son sel d'addition acide et sa conversion en palipéridone ou en son sel d'addition acide sans impliquer de catalyseur acide.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS METALLURGY ORGANIC CHEMISTRY |
| title | PREPARATION OF 3-(2-HYDROXY ETHYL)-9-HYDROXY-2-METHYL-4H-PYRIDO-[1,2-A]-PYRIMIDIN-4-ONE OR ITS ACID ADDITION SALT |
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