FEED SUPPLEMENT FOR MAMMALIAN CELL CULTURE AND METHODS OF USE

An improved feed supplement for culture of mammalian cells used to produce proteins is provided. The improved supplement is devoid of animal-derived components and protein hydrolysates. The invention also provides methods of using the supplement in production of a therapeutic proteins, such as an an...

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Bibliographische Detailangaben
Hauptverfasser:	MANAHAN, MATTHEW S, LING, WAI LAM WONG, OUYANG, ANLI
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	An improved feed supplement for culture of mammalian cells used to produce proteins is provided. The improved supplement is devoid of animal-derived components and protein hydrolysates. The invention also provides methods of using the supplement in production of a therapeutic proteins, such as an antibody. In some embodiments, the antibody is an anti-human IL-23p19 antibody. L'invention porte sur un supplément alimentaire amélioré pour une culture de cellules de mammifère utilisée pour produire des protéines. Le supplément amélioré est exempt de composants d'origine animale et d'hydrolysats de protéine. L'invention porte également sur des procédés d'utilisation du supplément dans la production de protéines thérapeutiques, telles qu'un anticorps. Dans certains modes de réalisation, l'anticorps est un anticorps anti-IL-23p19 humain.