ANTHRAQUINONE DIOXIMES AND USES THEREOF

Anthraquinone dioximes and their derivatives are disclosed for use in treatment of diseases, especially cancer, such as colon and colorectal cancer. Methods of preparing such derivatives are also presented. Compositions of these compounds, as well as metabolites of said compounds and their use in ge...

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Bibliographische Detailangaben
Hauptverfasser:	CHELLAPPAN, SHEELA, PADIA, JANAK, STROVEL, JEFFREY, ZUCK, KARINA, OHLER, ZOE, CHOLODY, WIESLAW, M, ZANG, YI, OHLER, NORMAN, E, WATTHEY, JEFFREY, W.H
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
Online-Zugang:	Volltext bestellen
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Beschreibung
Zusammenfassung:	Anthraquinone dioximes and their derivatives are disclosed for use in treatment of diseases, especially cancer, such as colon and colorectal cancer. Methods of preparing such derivatives are also presented. Compositions of these compounds, as well as metabolites of said compounds and their use in gene modulation are also described. L'invention porte sur des dioximes d'anthraquinone et sur leurs dérivés destinés à une utilisation dans le traitement de maladies, notamment du cancer, tel que le cancer du côlon et le cancer colorectal. L'invention porte également sur des procédés de préparation de tels dérivés. L'invention porte également sur des compositions de ces composés, ainsi que sur des métabolites desdits composés et sur leur utilisation dans la modulation génétique.