PROCESS FOR THE PURIFICATION OF HUMAN GROWTH HORMONE POLYPEPTIDES USING AFFINITY RESINS COMPRISING SPECIFIC LIGANDS
The present invention relates to a novel process for the purification of growth hormone polypeptides, e.g. recombinant human Growth Hormone. The process utilizes an affinity resin comprising a solid phase material having immobilized thereto one or more low-molecular weight synthetic ligands. The aff...
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| creator | RASMUSSEN, JAKOB EWALD JENSEN, KNUD JOERGEN ROICE, MICHAEL SCHIOEDT, CHRISTINE BRUUN ST. HILAIRE, PHAEDRIA MARIE |
| description | The present invention relates to a novel process for the purification of growth hormone polypeptides, e.g. recombinant human Growth Hormone. The process utilizes an affinity resin comprising a solid phase material having immobilized thereto one or more low-molecular weight synthetic ligands. The affinity resins enable the separation of Growth Hormone from closely related proteins.
La présente invention concerne un nouveau procédé pour l'épuration de polypeptides d'hormones de croissance, par exemple l'hormone de croissance humaine. Le procédé utilise une résine comportant un matériau de phase solide comprenant un ou des ligands de faible poids moléculaire qui y est immobilisé. Les résines d'affinité permettent la séparation de l'hormone de croissance de protéines intimement associées. |
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La présente invention concerne un nouveau procédé pour l'épuration de polypeptides d'hormones de croissance, par exemple l'hormone de croissance humaine. Le procédé utilise une résine comportant un matériau de phase solide comprenant un ou des ligands de faible poids moléculaire qui y est immobilisé. Les résines d'affinité permettent la séparation de l'hormone de croissance de protéines intimement associées.</description><language>eng ; fre</language><subject>CHEMISTRY ; METALLURGY ; ORGANIC CHEMISTRY ; PEPTIDES</subject><creationdate>2010</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20100520&DB=EPODOC&CC=WO&NR=2010055135A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76516</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20100520&DB=EPODOC&CC=WO&NR=2010055135A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>RASMUSSEN, JAKOB EWALD</creatorcontrib><creatorcontrib>JENSEN, KNUD JOERGEN</creatorcontrib><creatorcontrib>ROICE, MICHAEL</creatorcontrib><creatorcontrib>SCHIOEDT, CHRISTINE BRUUN</creatorcontrib><creatorcontrib>ST. HILAIRE, PHAEDRIA MARIE</creatorcontrib><title>PROCESS FOR THE PURIFICATION OF HUMAN GROWTH HORMONE POLYPEPTIDES USING AFFINITY RESINS COMPRISING SPECIFIC LIGANDS</title><description>The present invention relates to a novel process for the purification of growth hormone polypeptides, e.g. recombinant human Growth Hormone. The process utilizes an affinity resin comprising a solid phase material having immobilized thereto one or more low-molecular weight synthetic ligands. The affinity resins enable the separation of Growth Hormone from closely related proteins.
La présente invention concerne un nouveau procédé pour l'épuration de polypeptides d'hormones de croissance, par exemple l'hormone de croissance humaine. Le procédé utilise une résine comportant un matériau de phase solide comprenant un ou des ligands de faible poids moléculaire qui y est immobilisé. Les résines d'affinité permettent la séparation de l'hormone de croissance de protéines intimement associées.</description><subject>CHEMISTRY</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PEPTIDES</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2010</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNjEEKwjAQRbtxIeodBlwLrdIDhDRpBtpMmEkpXZUicSVaqPfHKh7A1efxHn-bLYFJGxGwxBCdgdAxWtQqInkgC65rlYeaqY8OHHFLfo2oGYIJESsj0An6GpS16DEOwGZlAU1tYPwqCUZ_PqHBWvlK9tnmNt2XdPjtLjtaE7U7pfk5pmWerumRXmNP57zI87IsLqUqLv9Vb61QOgQ</recordid><startdate>20100520</startdate><enddate>20100520</enddate><creator>RASMUSSEN, JAKOB EWALD</creator><creator>JENSEN, KNUD JOERGEN</creator><creator>ROICE, MICHAEL</creator><creator>SCHIOEDT, CHRISTINE BRUUN</creator><creator>ST. HILAIRE, PHAEDRIA MARIE</creator><scope>EVB</scope></search><sort><creationdate>20100520</creationdate><title>PROCESS FOR THE PURIFICATION OF HUMAN GROWTH HORMONE POLYPEPTIDES USING AFFINITY RESINS COMPRISING SPECIFIC LIGANDS</title><author>RASMUSSEN, JAKOB EWALD ; JENSEN, KNUD JOERGEN ; ROICE, MICHAEL ; SCHIOEDT, CHRISTINE BRUUN ; ST. HILAIRE, PHAEDRIA MARIE</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_WO2010055135A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2010</creationdate><topic>CHEMISTRY</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PEPTIDES</topic><toplevel>online_resources</toplevel><creatorcontrib>RASMUSSEN, JAKOB EWALD</creatorcontrib><creatorcontrib>JENSEN, KNUD JOERGEN</creatorcontrib><creatorcontrib>ROICE, MICHAEL</creatorcontrib><creatorcontrib>SCHIOEDT, CHRISTINE BRUUN</creatorcontrib><creatorcontrib>ST. HILAIRE, PHAEDRIA MARIE</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>RASMUSSEN, JAKOB EWALD</au><au>JENSEN, KNUD JOERGEN</au><au>ROICE, MICHAEL</au><au>SCHIOEDT, CHRISTINE BRUUN</au><au>ST. HILAIRE, PHAEDRIA MARIE</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>PROCESS FOR THE PURIFICATION OF HUMAN GROWTH HORMONE POLYPEPTIDES USING AFFINITY RESINS COMPRISING SPECIFIC LIGANDS</title><date>2010-05-20</date><risdate>2010</risdate><abstract>The present invention relates to a novel process for the purification of growth hormone polypeptides, e.g. recombinant human Growth Hormone. The process utilizes an affinity resin comprising a solid phase material having immobilized thereto one or more low-molecular weight synthetic ligands. The affinity resins enable the separation of Growth Hormone from closely related proteins.
La présente invention concerne un nouveau procédé pour l'épuration de polypeptides d'hormones de croissance, par exemple l'hormone de croissance humaine. Le procédé utilise une résine comportant un matériau de phase solide comprenant un ou des ligands de faible poids moléculaire qui y est immobilisé. Les résines d'affinité permettent la séparation de l'hormone de croissance de protéines intimement associées.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY METALLURGY ORGANIC CHEMISTRY PEPTIDES |
| title | PROCESS FOR THE PURIFICATION OF HUMAN GROWTH HORMONE POLYPEPTIDES USING AFFINITY RESINS COMPRISING SPECIFIC LIGANDS |
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