COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY DISORDERS

This invention relates to compounds of the Formula (I): (Chemical formula should be inserted here as it appears on abstract in paper form) (I) or a pharmaceutically acceptable salt thereof, which can be useful for the treatment of diseases or conditions mediated by MMPs, ADAMs, TACE, aggrecanase, TN...

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Hauptverfasser: GIRIJAVALLABHAN, VINAY, M, ROSNER, KRISTIN, E, CHEN, LEI, RICHARD, JUDSON, E, LAVEY, BRIAN, J, LI, DANSU, FELTZ, ROBERT, DAI, CHAOYANG, POPOVICI-MULLER, JANETA, SHANKAR, BANDARPALLE, B, KOZLOWSKI, JOSEPH, A, WONG, MICHAEL, K.C, KOSINSKI, ANETA, MARIA, TONG, LING, RIZVI, RAZIA, K, YU, WENSHENG, YANG, LIPING, ZHOU, GUOWEI, FIRE, LUKE, KIM, SEONG-HEON, SIDDIQUI, M., ARSHAD, YANG, DE-YI
Format: Patent
Sprache:eng ; fre
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Zusammenfassung:This invention relates to compounds of the Formula (I): (Chemical formula should be inserted here as it appears on abstract in paper form) (I) or a pharmaceutically acceptable salt thereof, which can be useful for the treatment of diseases or conditions mediated by MMPs, ADAMs, TACE, aggrecanase, TNF- or combinations thereof. Cette invention concerne des composés de Formule (I) ou un de leurs sels pharmaceutiquement acceptables, qui peuvent être utiles pour traiter les maladies ou les affections médiées par MMP, ADAM, TACE, l'aggrécanase, le TNF- ou des combinaisons ceux-ci.