COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY DISORDERS

This invention relates to compounds of the Formula (I)-(IX):, as defined herein, or a pharmaceutically acceptable salt, solvate or ester thereof, which can be useful for the treatment of diseases or conditions mediated by MMPs, ADAMs, TACE, aggrecanase, TNF- a combinations thereof. L'invention...

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Bibliographische Detailangaben
Hauptverfasser:	CHEN, LEI, RICHARD, JUDSON, E, LAVEY, BRIAN, J, LI, DANSU, WONG, MICHAEL, K., C, SHANKAR, BANDARPALLE, B, KOZLOWSKI, JOSEPH, A, KOSINSKI, ANETA, MARIA, TONG, LING, RIZVI, RAZIA, K, YU, WENSHENG, ZHOU, GUOWEI, ROSNER, KRISTEN, E, FIRE, LUKE, KIM, SEONG, HEON, YANG, DE-YI
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	This invention relates to compounds of the Formula (I)-(IX):, as defined herein, or a pharmaceutically acceptable salt, solvate or ester thereof, which can be useful for the treatment of diseases or conditions mediated by MMPs, ADAMs, TACE, aggrecanase, TNF- a combinations thereof. L'invention concerne des composés de la formule (I) à (IX), tels que définis dans la description, ou un sel, un solvate ou un ester pharmaceutiquement acceptable de ces composés, qui peuvent être utiles pour le traitement de maladies ou d'états pathologiques médiés par les MMP, ADAM, TACE, agrécanase, TNF-a ou leurs combinaisons.