COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY DISORDERS

This invention relates to compounds of the Formula (I) as described herein, or a pharmaceutically acceptable salt, solvate or ester thereof, which can be useful for the treatment of diseases or conditions mediated by MMPs, ADAMs, TACE, aggrecanase, TNF- or combinations thereof. L'invention conc...

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Hauptverfasser: CHEN, LEI, RICHARD, JUDSON, E, LI, DANSU, WONG, MICHAEL, K. C, SHANKAR, BANDARPALLE, B, KOZLOWSKI, JOSEPH, A, KOSINSKI, ANETA, MARIA, TONG, LING, RIZVI, RAZIA, K, YU, WENSHENG, LAVEY, BRIAN J, ZHOU, GUOWEI, ROSNER, KRISTEN, E, FIRE, LUKE, KIM, SEONG, HEON, YANG, DE-YI
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creator CHEN, LEI
RICHARD, JUDSON, E
LI, DANSU
WONG, MICHAEL, K. C
SHANKAR, BANDARPALLE, B
KOZLOWSKI, JOSEPH, A
KOSINSKI, ANETA, MARIA
TONG, LING
RIZVI, RAZIA, K
YU, WENSHENG
LAVEY, BRIAN J
ZHOU, GUOWEI
ROSNER, KRISTEN, E
FIRE, LUKE
KIM, SEONG, HEON
YANG, DE-YI
description This invention relates to compounds of the Formula (I) as described herein, or a pharmaceutically acceptable salt, solvate or ester thereof, which can be useful for the treatment of diseases or conditions mediated by MMPs, ADAMs, TACE, aggrecanase, TNF- or combinations thereof. L'invention concerne des composés représentés par la formule (I), ou un sel pharmaceutiquement acceptable, un solvate ou un ester de ceux-ci, qui peuvent être utilisés pour traiter des maladies ou des états induits par MMP, ADAM, TACE, l'agrécanase, TNF- ou par une combinaison de ceux-ci.
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C</au><au>SHANKAR, BANDARPALLE, B</au><au>KOZLOWSKI, JOSEPH, A</au><au>KOSINSKI, ANETA, MARIA</au><au>TONG, LING</au><au>RIZVI, RAZIA, K</au><au>YU, WENSHENG</au><au>LAVEY, BRIAN J</au><au>ZHOU, GUOWEI</au><au>ROSNER, KRISTEN, E</au><au>FIRE, LUKE</au><au>KIM, SEONG, HEON</au><au>YANG, DE-YI</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY DISORDERS</title><date>2010-05-27</date><risdate>2010</risdate><abstract>This invention relates to compounds of the Formula (I) as described herein, or a pharmaceutically acceptable salt, solvate or ester thereof, which can be useful for the treatment of diseases or conditions mediated by MMPs, ADAMs, TACE, aggrecanase, TNF- or combinations thereof. 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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY DISORDERS
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