COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY DISORDERS

This invention relates to compounds of the Formula (I) as described herein, or a pharmaceutically acceptable salt, solvate or ester thereof, which can be useful for the treatment of diseases or conditions mediated by MMPs, ADAMs, TACE, aggrecanase, TNF- or combinations thereof. L'invention conc...

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Bibliographische Detailangaben
Hauptverfasser:	CHEN, LEI, RICHARD, JUDSON, E, LI, DANSU, WONG, MICHAEL, K. C, SHANKAR, BANDARPALLE, B, KOZLOWSKI, JOSEPH, A, KOSINSKI, ANETA, MARIA, TONG, LING, RIZVI, RAZIA, K, YU, WENSHENG, LAVEY, BRIAN J, ZHOU, GUOWEI, ROSNER, KRISTEN, E, FIRE, LUKE, KIM, SEONG, HEON, YANG, DE-YI
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	This invention relates to compounds of the Formula (I) as described herein, or a pharmaceutically acceptable salt, solvate or ester thereof, which can be useful for the treatment of diseases or conditions mediated by MMPs, ADAMs, TACE, aggrecanase, TNF- or combinations thereof. L'invention concerne des composés représentés par la formule (I), ou un sel pharmaceutiquement acceptable, un solvate ou un ester de ceux-ci, qui peuvent être utilisés pour traiter des maladies ou des états induits par MMP, ADAM, TACE, l'agrécanase, TNF- ou par une combinaison de ceux-ci.