AZA-BENZIMIDAZOLONE CHYMASE INHIBITORS

Disclosed are small molecule inhibitors of the formula (I): and the pharmaceutical compositions thereof and processes of making the same. The compounds are useful in treating various diseases and conditions involving chymase. La présente invention concerne des inhibiteurs de petite taille de formule...

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Bibliographische Detailangaben
Hauptverfasser:	GUO, XIN, QIAN, KEVIN, CHUNGENG, NEMOTO, PETER, ALLEN, KIM, JIN, MI, LO, HO, YIN, EMMANUEL, MICHEL, JOSE
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	Disclosed are small molecule inhibitors of the formula (I): and the pharmaceutical compositions thereof and processes of making the same. The compounds are useful in treating various diseases and conditions involving chymase. La présente invention concerne des inhibiteurs de petite taille de formule (I) : et leurs compositions pharmaceutiques et leurs procédés de fabrication. Les composés sont utiles pour traiter des maladies et états divers impliquant la chymase.