METHOD OF USING FOXO3A POLYMORPHISMS AND HAPLOTYPES TO PREDICT AND PROMOTE HEALTHY AGING AND LONGEVITY

The invention provides methods and compositions relating to identification and use of genetic information from the FOXO3A gene that can be used for determining and increasing an individual's likelihood of longevity and of retaining physical and cognitive function during aging, and for determini...

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Bibliographische Detailangaben
Hauptverfasser:	CURB, J., DAVID, DONLON, TIMOTHY, ATCHISON, WILLCOX, BRADLEY, JOHN
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES ENZYMOLOGY INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING PHYSICS PROCESSES OF PREPARING SUCH COMPOSITIONS SPIRITS TESTING VINEGAR WINE
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Beschreibung
Zusammenfassung:	The invention provides methods and compositions relating to identification and use of genetic information from the FOXO3A gene that can be used for determining and increasing an individual's likelihood of longevity and of retaining physical and cognitive function during aging, and for determining and decreasing an individual's likelihood of developing a cardiovascular-, metabolic- or age-related disease, including coronary artery (heart) disease, stroke, cancer, chronic pulmonary disease, diabetes, Parkinson's disease and dementia. La présente invention porte sur des procédés et des compositions liés à l'identification et l'utilisation d'informations génétiques provenant du gène FOXO3A, qui peut être utilisé pour déterminer et augmenter la probabilité de longévité et de conservation de la fonction physique et cognitive durant le vieillissement d'un individu, et pour déterminer et diminuer la probabilité, pour un individu de développer une maladie cardiovasculaire, métabolique ou liée à l'âge, comprenant une coronaropathie, un accident cérébral vasculaire, un cancer, une maladie pulmonaire chronique, le diabète, la maladie de Parkinson et la démence.