CASPASE INHIBITORS AND USES THEREOF

This invention provides novel caspase inhibitors useful for prophylaxis or treatment of a number of pathologies, including, for example, Huntington's disease. In certain embodiments the inhibitors include inhibitors of casepase-3 and/or casepase-6. L'invention fournit de nouveaux inhibiteu...

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Bibliographische Detailangaben
Hauptverfasser:	ELLERBY, LISA, M, ELLMAN, JONATHAN, A, LEYVA, MELISSA, J
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CALCULATING CHEMISTRY COMPUTING COUNTING DATA PROCESSING SYSTEMS OR METHODS, SPECIALLY ADAPTED FORADMINISTRATIVE, COMMERCIAL, FINANCIAL, MANAGERIAL, SUPERVISORYOR FORECASTING PURPOSES HETEROCYCLIC COMPOUNDS METALLURGY ORGANIC CHEMISTRY PHYSICS SYSTEMS OR METHODS SPECIALLY ADAPTED FOR ADMINISTRATIVE,COMMERCIAL, FINANCIAL, MANAGERIAL, SUPERVISORY OR FORECASTINGPURPOSES, NOT OTHERWISE PROVIDED FOR
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Beschreibung
Zusammenfassung:	This invention provides novel caspase inhibitors useful for prophylaxis or treatment of a number of pathologies, including, for example, Huntington's disease. In certain embodiments the inhibitors include inhibitors of casepase-3 and/or casepase-6. L'invention fournit de nouveaux inhibiteurs de caspase utiles pour la prophylaxie ou le traitement de plusieurs pathologies, comprenant par exemple la maladie d'Huntington. Dans certains modes de réalisation, les inhibiteurs comprennent des inhibiteurs de caspase-3 et/ou caspase-6.