THERMALLY-ACTIVATABLE LIPOSOME COMPOSITIONS AND METHODS FOR IMAGING, DIAGNOSIS AND THERAPY

THERMALLY-ACTIVATABLE LIPOSOME COMPOSITIONS AND METHODS FOR IMAGING, DIAGNOSIS AND THERAPY

Disclosed are thermally-activatable liposomal compositions and methods for their use in the formulation and administration of therapeutic, prophylactic, and diagnostic agents. The disclosed liposome structures are capable of carrying a variety of biologically active reagents, and permitting their co...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: QIN, GUOTING, LI, ZHENG, LI, KING, CHUEN
Format: Patent
Sprache:eng ; fre
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:Disclosed are thermally-activatable liposomal compositions and methods for their use in the formulation and administration of therapeutic, prophylactic, and diagnostic agents. The disclosed liposome structures are capable of carrying a variety of biologically active reagents, and permitting their controlled release in vivo by exploiting properties of their thermoregulatable lability. La présente invention concerne des compositions liposomales thermo-activables et des procédés pour leur utilisation dans la formulation et l'administration d'agents thérapeutiques, prophylactiques et diagnostiques. Les structures de liposomes décrites sont capables de porter différents réactifs biologiquement actifs, et de permettre leur libération contrôlée in vivo par exploitation de leurs propriétés de labilité thermorégulable.