UNIVERSAL ANCHOR PEPTIDE FOR NANOPARTICLES

The present invention provides a substantially non-lytic, non-cytotoxic anchor peptide that is capable of stably inserting into lipid membranes. In particular, the invention provides nanoparticles comprising stably inserted anchor peptides, which may be conjugated to a variety of different cargo com...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: SOMAN, NEELESH, R, PAN, HUA, WICKLINE, SAMUEL, A, SCHLESINGER, PAUL, H, LANZA, GREGORY, M
Format: Patent
Sprache:eng ; fre
Schlagworte:
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:The present invention provides a substantially non-lytic, non-cytotoxic anchor peptide that is capable of stably inserting into lipid membranes. In particular, the invention provides nanoparticles comprising stably inserted anchor peptides, which may be conjugated to a variety of different cargo complexes. La présente invention concerne un peptide d'ancrage sensiblement non lytique, non cytotoxique qui peut être inséré de manière stable dans des membranes lipidiques. En particulier, l'invention concerne des nanoparticules comprenant des peptides d'ancrage insérés de manière stable, qui peuvent être conjugués à différents complexes de transport.