STYRYLBENZOFURAN DERIVATIVES AS INHIBITORS FOR BETA-AMYLOID FIBRIL FORMATION AND PREPARATION METHOD THEREOF

The present invention relates to a novel compound which efficiently inhibits the formation of beta-amyloid fibrils in the brain to be useful for preventing or treating a degenerative brain disease, a method for preparing same, and a pharmaceutical composition comprising same as an active ingredient....

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Hauptverfasser: KIM, MAENG SUP, AHN, YOUNG GIL, HWANG, HANA, YOO, KYUNG HO, BYUN, JI HUN, KIM, HYE YUN, KIM, DONG JIN, LEE, GWAN SUN, RYU, JIYEON, KIM, YOUNGSOO, LEE, JI HOON, LEE, MYOUNG-HWAN
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creator KIM, MAENG SUP
AHN, YOUNG GIL
HWANG, HANA
YOO, KYUNG HO
BYUN, JI HUN
KIM, HYE YUN
KIM, DONG JIN
LEE, GWAN SUN
RYU, JIYEON
KIM, YOUNGSOO
LEE, JI HOON
LEE, MYOUNG-HWAN
description The present invention relates to a novel compound which efficiently inhibits the formation of beta-amyloid fibrils in the brain to be useful for preventing or treating a degenerative brain disease, a method for preparing same, and a pharmaceutical composition comprising same as an active ingredient. La présente invention concerne un nouveau composé qui inhibe efficacement la formation de fibrilles d'amyloïde bêta dans le cerveau et destiné à être utilisé pour prévenir ou traiter une maladie cérébrale dégénérative, son procédé de préparation, et une composition pharmaceutique le comprenant comme principe actif.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title STYRYLBENZOFURAN DERIVATIVES AS INHIBITORS FOR BETA-AMYLOID FIBRIL FORMATION AND PREPARATION METHOD THEREOF
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