STYRYLBENZOFURAN DERIVATIVES AS INHIBITORS FOR BETA-AMYLOID FIBRIL FORMATION AND PREPARATION METHOD THEREOF
The present invention relates to a novel compound which efficiently inhibits the formation of beta-amyloid fibrils in the brain to be useful for preventing or treating a degenerative brain disease, a method for preparing same, and a pharmaceutical composition comprising same as an active ingredient....
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creator | KIM, MAENG SUP AHN, YOUNG GIL HWANG, HANA YOO, KYUNG HO BYUN, JI HUN KIM, HYE YUN KIM, DONG JIN LEE, GWAN SUN RYU, JIYEON KIM, YOUNGSOO LEE, JI HOON LEE, MYOUNG-HWAN |
description | The present invention relates to a novel compound which efficiently inhibits the formation of beta-amyloid fibrils in the brain to be useful for preventing or treating a degenerative brain disease, a method for preparing same, and a pharmaceutical composition comprising same as an active ingredient.
La présente invention concerne un nouveau composé qui inhibe efficacement la formation de fibrilles d'amyloïde bêta dans le cerveau et destiné à être utilisé pour prévenir ou traiter une maladie cérébrale dégénérative, son procédé de préparation, et une composition pharmaceutique le comprenant comme principe actif. |
format | Patent |
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La présente invention concerne un nouveau composé qui inhibe efficacement la formation de fibrilles d'amyloïde bêta dans le cerveau et destiné à être utilisé pour prévenir ou traiter une maladie cérébrale dégénérative, son procédé de préparation, et une composition pharmaceutique le comprenant comme principe actif.</description><language>eng ; fre</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><creationdate>2010</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20100401&DB=EPODOC&CC=WO&NR=2009151299A3$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20100401&DB=EPODOC&CC=WO&NR=2009151299A3$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>KIM, MAENG SUP</creatorcontrib><creatorcontrib>AHN, YOUNG GIL</creatorcontrib><creatorcontrib>HWANG, HANA</creatorcontrib><creatorcontrib>YOO, KYUNG HO</creatorcontrib><creatorcontrib>BYUN, JI HUN</creatorcontrib><creatorcontrib>KIM, HYE YUN</creatorcontrib><creatorcontrib>KIM, DONG JIN</creatorcontrib><creatorcontrib>LEE, GWAN SUN</creatorcontrib><creatorcontrib>RYU, JIYEON</creatorcontrib><creatorcontrib>KIM, YOUNGSOO</creatorcontrib><creatorcontrib>LEE, JI HOON</creatorcontrib><creatorcontrib>LEE, MYOUNG-HWAN</creatorcontrib><title>STYRYLBENZOFURAN DERIVATIVES AS INHIBITORS FOR BETA-AMYLOID FIBRIL FORMATION AND PREPARATION METHOD THEREOF</title><description>The present invention relates to a novel compound which efficiently inhibits the formation of beta-amyloid fibrils in the brain to be useful for preventing or treating a degenerative brain disease, a method for preparing same, and a pharmaceutical composition comprising same as an active ingredient.
La présente invention concerne un nouveau composé qui inhibe efficacement la formation de fibrilles d'amyloïde bêta dans le cerveau et destiné à être utilisé pour prévenir ou traiter une maladie cérébrale dégénérative, son procédé de préparation, et une composition pharmaceutique le comprenant comme principe actif.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2010</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNi70KwjAURrs4iPoOF5wL_cGh4425IYE2KTexUpdSJC6KFur7o6IP4PRxDudbJlcfeu5rQfbk1IHRgiQ2HQbTkQf0YKw2wgTHHpRjEBQwxaavnZGgjGBTf3zzPjgLaCW0TC3ylxsK2kkImpicWieLy3ib4-a3q2SrKOx1GqfHEOdpPMd7fA5HV2RZle_yoqqwLP-rXgqbOAQ</recordid><startdate>20100401</startdate><enddate>20100401</enddate><creator>KIM, MAENG SUP</creator><creator>AHN, YOUNG GIL</creator><creator>HWANG, HANA</creator><creator>YOO, KYUNG HO</creator><creator>BYUN, JI HUN</creator><creator>KIM, HYE YUN</creator><creator>KIM, DONG JIN</creator><creator>LEE, GWAN SUN</creator><creator>RYU, JIYEON</creator><creator>KIM, YOUNGSOO</creator><creator>LEE, JI HOON</creator><creator>LEE, MYOUNG-HWAN</creator><scope>EVB</scope></search><sort><creationdate>20100401</creationdate><title>STYRYLBENZOFURAN DERIVATIVES AS INHIBITORS FOR BETA-AMYLOID FIBRIL FORMATION AND PREPARATION METHOD THEREOF</title><author>KIM, MAENG SUP ; AHN, YOUNG GIL ; HWANG, HANA ; YOO, KYUNG HO ; BYUN, JI HUN ; KIM, HYE YUN ; KIM, DONG JIN ; LEE, GWAN SUN ; RYU, JIYEON ; KIM, YOUNGSOO ; LEE, JI HOON ; LEE, MYOUNG-HWAN</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_WO2009151299A33</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2010</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><toplevel>online_resources</toplevel><creatorcontrib>KIM, MAENG SUP</creatorcontrib><creatorcontrib>AHN, YOUNG GIL</creatorcontrib><creatorcontrib>HWANG, HANA</creatorcontrib><creatorcontrib>YOO, KYUNG HO</creatorcontrib><creatorcontrib>BYUN, JI HUN</creatorcontrib><creatorcontrib>KIM, HYE YUN</creatorcontrib><creatorcontrib>KIM, DONG JIN</creatorcontrib><creatorcontrib>LEE, GWAN SUN</creatorcontrib><creatorcontrib>RYU, JIYEON</creatorcontrib><creatorcontrib>KIM, YOUNGSOO</creatorcontrib><creatorcontrib>LEE, JI HOON</creatorcontrib><creatorcontrib>LEE, MYOUNG-HWAN</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>KIM, MAENG SUP</au><au>AHN, YOUNG GIL</au><au>HWANG, HANA</au><au>YOO, KYUNG HO</au><au>BYUN, JI HUN</au><au>KIM, HYE YUN</au><au>KIM, DONG JIN</au><au>LEE, GWAN SUN</au><au>RYU, JIYEON</au><au>KIM, YOUNGSOO</au><au>LEE, JI HOON</au><au>LEE, MYOUNG-HWAN</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>STYRYLBENZOFURAN DERIVATIVES AS INHIBITORS FOR BETA-AMYLOID FIBRIL FORMATION AND PREPARATION METHOD THEREOF</title><date>2010-04-01</date><risdate>2010</risdate><abstract>The present invention relates to a novel compound which efficiently inhibits the formation of beta-amyloid fibrils in the brain to be useful for preventing or treating a degenerative brain disease, a method for preparing same, and a pharmaceutical composition comprising same as an active ingredient.
La présente invention concerne un nouveau composé qui inhibe efficacement la formation de fibrilles d'amyloïde bêta dans le cerveau et destiné à être utilisé pour prévenir ou traiter une maladie cérébrale dégénérative, son procédé de préparation, et une composition pharmaceutique le comprenant comme principe actif.</abstract><oa>free_for_read</oa></addata></record> |
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subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES |
title | STYRYLBENZOFURAN DERIVATIVES AS INHIBITORS FOR BETA-AMYLOID FIBRIL FORMATION AND PREPARATION METHOD THEREOF |
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