STYRYLBENZOFURAN DERIVATIVES AS INHIBITORS FOR BETA-AMYLOID FIBRIL FORMATION AND PREPARATION METHOD THEREOF

The present invention relates to a novel compound which efficiently inhibits the formation of beta-amyloid fibrils in the brain to be useful for preventing or treating a degenerative brain disease, a method for preparing same, and a pharmaceutical composition comprising same as an active ingredient....

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Bibliographische Detailangaben
Hauptverfasser:	KIM, MAENG SUP, AHN, YOUNG GIL, HWANG, HANA, YOO, KYUNG HO, BYUN, JI HUN, KIM, HYE YUN, KIM, DONG JIN, LEE, GWAN SUN, RYU, JIYEON, KIM, YOUNGSOO, LEE, JI HOON, LEE, MYOUNG-HWAN
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:	The present invention relates to a novel compound which efficiently inhibits the formation of beta-amyloid fibrils in the brain to be useful for preventing or treating a degenerative brain disease, a method for preparing same, and a pharmaceutical composition comprising same as an active ingredient. La présente invention concerne un nouveau composé qui inhibe efficacement la formation de fibrilles d'amyloïde bêta dans le cerveau et destiné à être utilisé pour prévenir ou traiter une maladie cérébrale dégénérative, son procédé de préparation, et une composition pharmaceutique le comprenant comme principe actif.