PYRAZOLOSPIROKETONE ACETYL-C0A CARBOXYLASE INHIBITORS

The invention provides compounds of Formula (1) or a pharmaceutically acceptable salt of said compound, wherein R1, R2, and R3 are as described herein; pharmaceutical compositions thereof; and the use thereof in treating diseases, conditions or disorders modulated by the inhibition of acetyl-CoA car...

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Bibliographische Detailangaben
Hauptverfasser:	FREEMAN-COOK, KEVIN DANIEL, GRIFFITH, DAVID, ANDREW, CORBETT, JEFFREY, WAYNE, PHILLION, DENNIS, PAUL, ELLIOTT, RICHARD, LOUIS
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The invention provides compounds of Formula (1) or a pharmaceutically acceptable salt of said compound, wherein R1, R2, and R3 are as described herein; pharmaceutical compositions thereof; and the use thereof in treating diseases, conditions or disorders modulated by the inhibition of acetyl-CoA carboxylase enzyme(s) in an animal. La présente invention concerne des composés de formule (1) ou un sel pharmaceutiquement acceptable dudit composé, dans laquelle R1, R2, et R3 sont tels que décrits ici; l'invention concerne également des compositions pharmaceutiques de ceux-ci; et l'utilisation de ceux-ci dans le traitement de maladies, de conditions ou de troubles modulés par l'inhibition del'enzyme ou des enzymes acétyl-CoA carboxylase chez un animal.