PROLYL HYDROXYLASE INHIBITORS

The invention described herein relates to certain benzimidazol-4-ylcarboxamide derivatives of formula (I) which are antagonists of HIF prolyl hydroxylases and are useful for treating diseases benefiting from the inhibition of this enzyme, anemia being one example. La présente invention concerne cert...

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Bibliographische Detailangaben
Hauptverfasser:	FITCH, DUKE, M, CHAI, DEPING
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	AGRICULTURE ANIMAL HUSBANDRY BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES, AS HERBICIDES FISHING FORESTRY HUMAN NECESSITIES HUNTING HYGIENE MEDICAL OR VETERINARY SCIENCE PEST REPELLANTS OR ATTRACTANTS PLANT GROWTH REGULATORS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTSTHEREOF TRAPPING
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Beschreibung
Zusammenfassung:	The invention described herein relates to certain benzimidazol-4-ylcarboxamide derivatives of formula (I) which are antagonists of HIF prolyl hydroxylases and are useful for treating diseases benefiting from the inhibition of this enzyme, anemia being one example. La présente invention concerne certains dérivés du benzimidazol-4-ylcarboxamide de formule (I) qui sont des antagonistes des prolylhydroxylases de HIF et qui se révèlent utiles dans le cadre du traitement de maladies pour lesquelles on a intérêt à avoir une inhibition desdites enzymes, dont, par exemple, l'anémie.