CRYSTALLINE FORM OF(7-[4-(4-FLUOROPHENYL)-6-ISOPROPYL-2-(N- METHYL-N-METHYLSULFONYLAMINO)PYRIMIDIN-5-YL]-(3R,5S)- DIHYDROXY-(E)-6-HEPTENOIC ACID INTERMEDIATE, PROCESS FOR PREPARING THE SAME AND USE THEREOF

CRYSTALLINE FORM OF(7-[4-(4-FLUOROPHENYL)-6-ISOPROPYL-2-(N- METHYL-N-METHYLSULFONYLAMINO)PYRIMIDIN-5-YL]-(3R,5S)- DIHYDROXY-(E)-6-HEPTENOIC ACID INTERMEDIATE, PROCESS FOR PREPARING THE SAME AND USE THEREOF

Disclosed herein is a crystalline form of methyl 7-[4-(4-flourophenyl)-6- isopropyl-2-(N-methyl-N-methylsulfonylamino)-pyrimidin-5-yl]-(3R)-3-hydroxy-5-oxo- (E)-6-heptenate (rosuvastatin intermediate), process for producing the same and using the same for producing rosuvastatin or pharmaceutically a...

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Bibliographische Detailangaben
Hauptverfasser: DATTA, DEBASHISH, RAY, PURNA, CHANDRA, SETHI, MADHURESH, MAHAJAN, SANJAY
Format: Patent
Sprache:eng ; fre
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Zusammenfassung:Disclosed herein is a crystalline form of methyl 7-[4-(4-flourophenyl)-6- isopropyl-2-(N-methyl-N-methylsulfonylamino)-pyrimidin-5-yl]-(3R)-3-hydroxy-5-oxo- (E)-6-heptenate (rosuvastatin intermediate), process for producing the same and using the same for producing rosuvastatin or pharmaceutically acceptable salts thereof. L'invention porte sur une forme cristalline du 7-[4-(4-fluorophényl)-6-isopropyl-2-(N-méthyl-N-méthylsulfonylamino)pyrimidin-5-yl]-(3R)-3-hydroxy-5-oxo-(E)-6-hepténate de méthyle (intermédiaire de la rosuvastatine), sur un procédé pour la fabrication de celle-ci et sur l'utilisation de celle-ci pour la fabrication de rosuvastatine ou de sels pharmaceutiquement acceptables de celle-ci.