PHENYLSULFONAMIDE-SUBSTITUTED, PYRAZOLO[1, 5-A]PYRIMIDINES, METHODS FOR PREPARATION AND USES THEREOF

PHENYLSULFONAMIDE-SUBSTITUTED, PYRAZOLO[1, 5-A]PYRIMIDINES, METHODS FOR PREPARATION AND USES THEREOF

Phenylsulfonamide substituted, pyrazolo[1,5-a]pyrimidines are described. The compounds of the invention selectively inhibit Raf kinase activity and are useful for treating disorders associated with Raf kinases. Formula (I) L'invention porte sur des pyrazolo[1,5-a]pyrimidines substituées par phé...

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Bibliographische Detailangaben
Hauptverfasser: DUTIA, MINU DHANJISHA, DIAMANTIDIS, GEORGE, BERGER, DAN MAARTEN, NORTON, EMILY BOUCHER, LEVIN, JEREMY IAN
Format: Patent
Sprache:eng ; fre
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Zusammenfassung:Phenylsulfonamide substituted, pyrazolo[1,5-a]pyrimidines are described. The compounds of the invention selectively inhibit Raf kinase activity and are useful for treating disorders associated with Raf kinases. Formula (I) L'invention porte sur des pyrazolo[1,5-a]pyrimidines substituées par phénylsulfonamide. Les composés de l'invention inhibent de façon sélective l'activité Raf kinase et sont utiles pour le traitement de troubles associés avec des Raf kinases. Formule (I)