PHOSPHODIESTERASE 10 CATALYTIC DOMAIN CRYSTALS

The invention provides a crystal or co-crystal of PDE10 catalytic domain, which crystallizes in the rhombohedral space group H3 and their uses in drug design. Cette invention concerne un cristal ou un co-cristal du domaine catalytique du PDE10, qui se cristallise dans le groupe H3 de l'espace r...

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Bibliographische Detailangaben
Hauptverfasser:	SCHLATTER, DANIEL, WANG, SANDRA, M, RUDOLPH, MARKUS, SHAW, DAVID, BENZ, JOERG, WEBER, MARTIN, JOSEPH, CATHERINE
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	AFTER-TREATMENT OF SINGLE CRYSTALS OR A HOMOGENEOUSPOLYCRYSTALLINE MATERIAL WITH DEFINED STRUCTURE APPARATUS THEREFOR BEER BIOCHEMISTRY CALCULATING CHEMISTRY COMPOSITIONS THEREOF COMPUTING COUNTING CRYSTAL GROWTH CULTURE MEDIA ELECTRIC DIGITAL DATA PROCESSING ENZYMOLOGY INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTEDFOR SPECIFIC APPLICATION FIELDS INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PHYSICS PRODUCTION OF A HOMOGENEOUS POLYCRYSTALLINE MATERIAL WITHDEFINED STRUCTURE PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS REFINING BY ZONE-MELTING OF MATERIAL SINGLE CRYSTALS OR HOMOGENEOUS POLYCRYSTALLINE MATERIAL WITHDEFINED STRUCTURE SINGLE-CRYSTAL-GROWTH SPIRITS TESTING UNIDIRECTIONAL SOLIDIFICATION OF EUTECTIC MATERIAL ORUNIDIRECTIONAL DEMIXING OF EUTECTOID MATERIAL VINEGAR WINE
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Beschreibung
Zusammenfassung:	The invention provides a crystal or co-crystal of PDE10 catalytic domain, which crystallizes in the rhombohedral space group H3 and their uses in drug design. Cette invention concerne un cristal ou un co-cristal du domaine catalytique du PDE10, qui se cristallise dans le groupe H3 de l'espace rhomboédrique et ses utilisations dans la conception de médicaments.