PROCESS FOR PREPARATION OF (S) (N-[[3-[3-FLUORO-4-(4-MORPHOLINYL) HEN L -2-OXO-5-OXAZOLIDIN L METHYL]ACETAMIDE

The present invention provides novel process for preparation of (S)-N-[[3-[3-Fluoro-4-(4- morpholinyl)phenyl]-2-oxo-5-oxazolidinyl] methyl] -acetamide which comprises combining (R)-N-[3-[3-fluoro-4-morpholinyl phenyl]-2-oxo-5-oxazolidinyl]methylazide in suitable solvent, acetylating agent and acid i...

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Bibliographische Detailangaben
Hauptverfasser: SAWANT, KAMLESH, DIGAMBAR, BHATTACHARYYA, ANINDYA, SIBNATH, SATHE, DHANANJAY, GOVIND, BHISE, NANDU, BABAN, NAIDU, AVINASH, VANKATRAMAN, NAIK, TUSHAR, ANIL
Format: Patent
Sprache:eng ; fre
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Zusammenfassung:The present invention provides novel process for preparation of (S)-N-[[3-[3-Fluoro-4-(4- morpholinyl)phenyl]-2-oxo-5-oxazolidinyl] methyl] -acetamide which comprises combining (R)-N-[3-[3-fluoro-4-morpholinyl phenyl]-2-oxo-5-oxazolidinyl]methylazide in suitable solvent, acetylating agent and acid in presence of a catalyst. La présente invention concerne un nouveau processus de préparation de (S)-N-[[3-[3-Fluoro-4-(4- morpholinyl)phényl]-2-oxo-5-oxazolidinyle] méthyl] -acétamide qui consiste à combiner (R)-N-[3-[3-fluoro-4-morpholinyle phényl]-2-oxo-5-oxazolidinyl]méthylazide dans un solvant adapté, un agent d'acétylation et un acide en présence d'un catalyseur.