A NON-DESENSITIZING MUTANT OF THE TRANSIENT RECEPTOR POTENTIAL TRPMS ION CHANNEL

There exists a need in the art for high throughput screening assays that can identify compounds that specifically modulate the activity of fast-acting ion channels, such as TRPM5. Current methods, especially electrophysiological, suffer from a lack of sensitivity, rapid signal loss, low throughput,...

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Bibliographische Detailangaben

Hauptverfasser:	PALMER, ROY, KYLE, CERNE, ROK, BRYANT, ROBERT, W, LEE, SEUNGHUN, PAUL, BUBER, M.N, TULU, BAKAJ, IVONA
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING METALLURGY ORGANIC CHEMISTRY PEPTIDES PHYSICS TESTING
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